Molecular structure of 3-Methyl Hippuric Acid, CAS Number: 27115-49-7
3-Methyl Hippuric Acid (CAS 27115-49-7)
Alternate Names:
N-(3-Methylbenzoyl)glycine
CAS Number:
27115-49-7
Molecular Weight:
193.20
Molecular Formula:
C10H11NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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3-Methyl Hippuric Acid is a metabolite that is formed in the liver through the conjugation of benzoic acid with glycine. It is excreted in the urine and serves as a marker for exposure to toluene, a common industrial solvent. Toluene is metabolized to benzoic acid, which is conjugated with glycine to form 3-Methyl Hippuric Acid. This process allows for the elimination of toluene. The presence of 3-Methyl Hippuric Acid in urine samples can therefore indicate exposure to toluene, making it a useful biomarker in occupational and environmental health studies. Its function as a biomarker allows for the assessment of toluene exposure levels in individuals, without directly measuring the presence of toluene itself.
3-Methyl Hippuric Acid (CAS 27115-49-7) References
- The application of global sensitivity analysis in the development of a physiologically based pharmacokinetic model for m-xylene and ethanol co-exposure in humans. | Loizou, GD., et al. 2015. Front Pharmacol. 6: 135. PMID: 26175688
- An amino-functionalized mesoporous silica (KIT-6) as a sorbent for dispersive and ultrasonication-assisted micro solid phase extraction of hippuric acid and methylhippuric acid, two biomarkers for toluene and xylene exposure. | Behbahani, M., et al. 2018. Mikrochim Acta. 185: 505. PMID: 30311000
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Methyl Hippuric Acid, 1 g | sc-216491 | 1 g | $52.00 | |||
3-Methyl Hippuric Acid, 25 g | sc-216491A | 25 g | $132.00 | |||
3-Methyl Hippuric Acid, 100 g | sc-216491B | 100 g | $411.00 |