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3-Methyl-d3-adenine is an adenine derivative that is N-methylated with a deuterated methyl group. In studies investigating N-methylations of DNA bases, use of deuterated methylating agents allows for monitoring of alkylation patterns with mass spectrometry. 3-Methyl-d3-adenine is potentially useful as a reference sample for identifying adenine alkylations in such studies.
1. Shuker, D.E., et al. 1993. Environ. Health Perspect. 101: 151-153. PMID: 8143609
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