3-Methyl-8-(2′-deoxy-β-D-ribofuranosyl)isoxanthopterin (CAS 170379-51-8)
Alternate Names:
3-MI
CAS Number:
170379-51-8
Molecular Weight:
309.28
Molecular Formula:
C12H15N5O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3-Methyl-8-(2′-deoxy-β-D-ribofuranosyl)isoxanthopterin, scientifically known as 8-DIR-Me, is a derivative of isoxanthopterin, a compound found naturally. This modified form is believed to exert its effects by boosting the function of DNA repair enzymes, thereby aiding in DNA repair mechanisms. Additionally, it has demonstrated the ability to hinder the activity of enzymes associated with the growth of cancer cells.
3-Methyl-8-(2′-deoxy-β-D-ribofuranosyl)isoxanthopterin (CAS 170379-51-8) References
- HU binding to DNA: evidence for multiple complex formation and DNA bending. | Wojtuszewski, K., et al. 2001. Biochemistry. 40: 2588-98. PMID: 11327882
- Use of a Pteridine Moiety to Track DNA Uptake in Cells. | Costa, JA., et al. 2013. Pteridines. 23: 81-89. PMID: 24465092
- Modified oligonucleotides: synthesis and strategy for users. | Verma, S. and Eckstein, F. 1998. Annu Rev Biochem. 67: 99-134. PMID: 9759484
- On the Feasibility of Single-Molecule Detection of the Guanosine-Analogue 3-MI | Jason E. Sanabia, Lori S. Goldner, Pierre-Antoine Lacaze, and Mary E. Hawkins. 2004,. J. Phys. Chem. B. 108, 39,: 15293–15300.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Methyl-8-(2′-deoxy-β-D-ribofuranosyl)isoxanthopterin, 1 mg | sc-216507 | 1 mg | $290.00 |