Date published: 2025-9-24

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3-Methoxy-2-methylaniline (CAS 19500-02-8)

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Alternate Names:
2-Methyl-m-anisidine; 2-Methoxy-6-aminotoluene; 2-Methyl-3-methoxyaniline
Application:
3-Methoxy-2-methylaniline is a derivative used in preparation of indoles, indazoles and quinoline antiviral agents
CAS Number:
19500-02-8
Molecular Weight:
137.18
Molecular Formula:
C8H11NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Methoxy-2-methylaniline is an aromatic amine derivative in which the aniline structure is substituted with a methoxy group at the 3-position and a methyl group at the 2-position. This structure makes it an important compound in various fields of chemical research, particularly in organic synthesis and material science. In scientific research, 3-Methoxy-2-methylaniline is frequently used as an intermediate in the synthesis of complex organic molecules. Its structure is particularly useful for introducing methoxy and methyl groups into aromatic systems, which can significantly alter the electronic and steric properties of these systems. This makes it a valuable building block for the synthesis of dyes, and agrochemicals, although its use in these applications is purely at the research level. The methoxy and methyl substituents on the aniline ring influence the reactivity of the amine group, often making it less nucleophilic than aniline itself. This property is exploited in various organic transformations, where 3-Methoxy-2-methylaniline can undergo electrophilic substitution reactions more selectively. Additionally, 3-Methoxy-2-methylaniline has been used in the study of aniline polymerization and copolymerization processes. Researchers explore how the substitution pattern affects the polymerization kinetics and the properties of the resulting polymers. This research is crucial for developing new materials with tailored electrical, optical, and mechanical properties.


3-Methoxy-2-methylaniline (CAS 19500-02-8) References

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  5. Potent Dual Inhibitors of Steroid Sulfatase and 17β-Hydroxysteroid Dehydrogenase Type 1 with a Suitable Pharmacokinetic Profile for In Vivo Proof-of-Principle Studies in an Endometriosis Mouse Model.  |  Salah, M., et al. 2023. J Med Chem. 66: 8975-8992. PMID: 37369108
  6. Synthesis of 2-(4-Isopropylthiazol-2-yl)-7-methoxy-8-methylquinolin-4-ol; A Quinoline Building Block for Simeprevir Synthesis[J].  |  Radl S, Rezkova H, Obadalova I. 2014: Synthesis,. 899-908.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Methoxy-2-methylaniline, 1 g

sc-394124
1 g
$84.00