Molecular structure of 3-Mercaptopicolinic Acid, Hydrochloride, CAS Number: 320386-54-7
3-Mercaptopicolinic Acid, Hydrochloride (CAS 320386-54-7)
See product citations (7)
Application:
3-Mercaptopicolinic Acid, Hydrochloride is a potent gluconeogenesis inhibitor
CAS Number:
320386-54-7
Molecular Weight:
191.64
Molecular Formula:
C6H6ClNO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3-Mercaptopicolinic Acid, Hydrochloride (3-MPA HCl) is a potent gluconeogenesis inhibitor. In perfused rat livers, gluconeogenesis was inhibited when lactate, pyruvate, or alanine served as substrate, but not with fructose, suggesting phosphoenolpyruvate carboxykinase as the site of inhibition. 3-Mercaptopicolinic Acid, Hydrochloride has been used in studies of DNA and RNA, enzyme kinetics, protein structure, and enzyme inhibition.
3-Mercaptopicolinic Acid, Hydrochloride (CAS 320386-54-7) References
- 3-Mercaptopicolinic acid, a preferential inhibitor of the cytosolic phosphoenolpyruvate carboxykinase. | Robinson, BH. and Oei, J. 1975. FEBS Lett. 58: 12-5. PMID: 1225570
- Inhibition of Pig Phosphoenolpyruvate Carboxykinase Isoenzymes by 3-Mercaptopicolinic Acid and Novel Inhibitors. | Hidalgo, J., et al. 2016. PLoS One. 11: e0159002. PMID: 27391465
- Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis. | Sadiku, P., et al. 2021. Cell Metab. 33: 411-423.e4. PMID: 33306983
- Mercaptopyridinecarboxylic acids, synthesis and hypoglycemic activity. | Blank, B., et al. 1974. J Med Chem. 17: 1065-71. PMID: 4417798
- 3-mercaptopicolinic acid, an inhibitor of gluconeogenesis. | DiTullio, NW., et al. 1974. Biochem J. 138: 387-94. PMID: 4429541
Inhibitor of:
CPS2, FPGS, MCCA, PEPCK-C, and PEPCK-M.Activator of:
PDK4.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Mercaptopicolinic Acid, Hydrochloride, 1 g | sc-206655 | 1 g | $296.00 |