Date published: 2026-4-25

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3-Isochromanone (CAS 4385-35-7)

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CAS Number:
4385-35-7
Molecular Weight:
148.16
Molecular Formula:
C9H8O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Isochromanone (3-ICN) is a naturally occurring heterocyclic aromatic compound that finds application in both scientific research and various industrial endeavors. Its versatility makes it a promising candidate for research and development, owing to its diverse biological effects. Furthermore, it has contributed significantly to studying important biochemical pathways, such as the synthesis of serotonin and the regulation of gene expression. Although the precise mechanism of action for 3-Isochromanone remains elusive, it is believed to involve the inhibition of monoamine oxidase (MAO) enzymes. These enzymes are responsible for breaking down neurotransmitters like serotonin, and by inhibiting them, 3-Isochromanone can lead to elevated serotonin levels. Additionally, this compound may act to interact with other enzymes involved in essential biochemical pathways, like cytochrome P450 enzymes. As research progresses, further insights into the potential of 3-Isochromanone and its applications in both scientific exploration and industry are likely to emerge. Its diverse effects and ability to interact with vital biochemical pathways continue to make it an intriguing subject for future investigations and development.


3-Isochromanone (CAS 4385-35-7) References

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  7. Pd(II)-catalyzed decarboxylative acylation of phenylacetamides with α-oxocarboxylic acids via C-H bond activation.  |  Park, J., et al. 2013. Chem Commun (Camb). 49: 1654-6. PMID: 23334232
  8. Catalytic Asymmetric Conjugate Addition of Carboxylic Acids via Oxa-Michael Reaction of Peroxy Hemiacetals followed by Kornblum DeLaMare Fragmentation.  |  Parhi, B., et al. 2016. Org Lett. 18: 5220-5223. PMID: 27690466
  9. Enantioselective Synthesis of α-Allyl-α-aryldihydrocoumarins and 3-Isochromanones via Pd-Catalyzed Decarboxylative Asymmetric Allylic Alkylation.  |  Akula, R. and Guiry, PJ. 2016. Org Lett. 18: 5472-5475. PMID: 27780358
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Isochromanone, 1 g

sc-231776
1 g
$31.00