Date published: 2025-9-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

3-Hydroxypropionic acid (CAS 503-66-2)

5.0(1)
Write a reviewAsk a question

Application:
3-Hydroxypropionic acid is a three carbon non-chiral compound used as a building block for industrial chemicals
CAS Number:
503-66-2
Molecular Weight:
90.08
Molecular Formula:
C3H6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

3-Hydroxypropionic acid is a three carbon non-chiral compound used as a building block to derive many important industrial chemicals. Studies indicate that 3-Hydroxypropionic acid can be synthesized from glycerol using the recombinant Escherichia coli SH254, which expresses glycerol dehydratase (DhaB) and aldehyde dehydrogenase (AldH). Structurally, the carboxyl group and the beta hydroxyl group make 3-Hydroxypropionic acid very reactive. 3-Hydroxypropionic acid is a novel substrate in the production of polymers because this compound produces biodegradable polymers, which can replace existing polymers currently used in industry. Biologically, 3-Hydroxypropionic acid may be used to produce surgical biocomposite material and drug release material.


3-Hydroxypropionic acid (CAS 503-66-2) References

  1. Biosynthetic pathways for 3-hydroxypropionic acid production.  |  Jiang, X., et al. 2009. Appl Microbiol Biotechnol. 82: 995-1003. PMID: 19221732
  2. Development of recombinant Klebsiella pneumoniae ∆dhaT strain for the co-production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol.  |  Ashok, S., et al. 2011. Appl Microbiol Biotechnol. 90: 1253-65. PMID: 21336929
  3. Enhancement of 3-hydroxypropionic acid production from glycerol by using a metabolic toggle switch.  |  Tsuruno, K., et al. 2015. Microb Cell Fact. 14: 155. PMID: 26438162
  4. 3-Hydroxypropionic acid production by recombinant Escherichia coli ZJU-3HP01 using glycerol-glucose dual-substrate fermentative strategy.  |  Niu, K., et al. 2017. Biotechnol Appl Biochem. 64: 572-578. PMID: 27189262
  5. Exploiting tandem repetitive promoters for high-level production of 3-hydroxypropionic acid.  |  Zhao, P., et al. 2019. Appl Microbiol Biotechnol. 103: 4017-4031. PMID: 30927024
  6. Production of 3-hydroxypropionic acid from acetate using metabolically-engineered and glucose-grown Escherichia coli.  |  Lama, S., et al. 2021. Bioresour Technol. 320: 124362. PMID: 33186840
  7. Psychrophile-based simple biocatalysts for effective coproduction of 3-hydroxypropionic acid and 1,3-propanediol.  |  Mojarrad, M., et al. 2021. Biosci Biotechnol Biochem. 85: 728-738. PMID: 33624773
  8. 3-Hydroxypropionic acid contributes to the antibacterial activity of glycerol metabolism by the food microbe Limosilactobacillus reuteri.  |  Liang, N., et al. 2021. Food Microbiol. 98: 103720. PMID: 33875197
  9. Benchmarking recombinant Pichia pastoris for 3-hydroxypropionic acid production from glycerol.  |  Fina, A., et al. 2021. Microb Biotechnol. 14: 1671-1682. PMID: 34081409
  10. One stone two birds: Biosynthesis of 3-hydroxypropionic acid from CO2 and syngas-derived acetic acid in Escherichia coli.  |  Lai, N., et al. 2021. Synth Syst Biotechnol. 6: 144-152. PMID: 34278012
  11. Efficient 3-hydroxypropionic acid production by Acetobacter sp. CIP 58.66 through a feeding strategy based on pH control.  |  de Fouchécour, F., et al. 2021. AMB Express. 11: 130. PMID: 34542700
  12. Improvement of 3-hydroxypropionic acid tolerance in Klebsiella pneumoniae by novel transporter YohJK.  |  Nguyen-Vo, TP., et al. 2022. Bioresour Technol. 346: 126613. PMID: 34954352
  13. Enhanced 3-Hydroxypropionic Acid Production From Acetate via the Malonyl-CoA Pathway in Corynebacterium glutamicum.  |  Chang, Z., et al. 2021. Front Bioeng Biotechnol. 9: 808258. PMID: 35096794
  14. Efficient biosynthesis of 3-hydroxypropionic acid from ethanol in metabolically engineered Escherichia coli.  |  Lu, J., et al. 2022. Bioresour Technol. 363: 127907. PMID: 36087655
  15. Improving 3-hydroxypropionic acid production in E. coli by in silico prediction of new metabolic targets.  |  Chaves, GL., et al. 2022. N Biotechnol. 72: 80-88. PMID: 36272546

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Hydroxypropionic acid, 10 g

sc-261015
10 g
$306.00

3-Hydroxypropionic acid, 25 g

sc-261015A
25 g
$612.00