Date published: 2026-5-29

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3-Hydroxyphenethylamine hydrochloride (CAS 3458-98-8)

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Application:
3-Hydroxyphenethylamine hydrochloride is a compound also known as 2-(3-Hydroxyphenyl)ethanamine
CAS Number:
3458-98-8
Molecular Weight:
173.64
Molecular Formula:
C8H12ClNO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Hydroxyphenethylamine hydrochloride, also known as 3-(2-Aminoethyl)phenol hydrochloride or 2-aminoethylphenol hydrochloride, is a versatile chemical compound widely used in laboratory experiments. It is a white powder that readily dissolves in water and ethanol, with a melting point of approximately 150°C. This compound is valued for its broad applications in scientific research, particularly in understanding drug mechanisms and studying the effects of various compounds. In drug research, 3-Hydroxyphenethylamine hydrochloride has contributed to uncovering the mechanisms of drugs like phenytoin and fluconazole, used as anticonvulsant and antifungal agents, respectively. It has also aided in investigating the biochemical and physiological effects of compounds such as the anesthetic propofol on the central nervous system. Although the precise mechanism of action is not fully elucidated, it is believed that 3-Hydroxyphenethylamine hydrochloride acts as a proton donor, facilitating the formation of hydrogen bonds between molecules. This property enhances the solubility of specific compounds and accelerates certain chemical reactions. Furthermore, it is thought to act as a chelating agent, forming complexes with metal ions, which proves valuable in various scientific experiments.


3-Hydroxyphenethylamine hydrochloride (CAS 3458-98-8) References

  1. Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.  |  Bressi, JC., et al. 2000. J Med Chem. 43: 4135-50. PMID: 11063610
  2. A simple and selective fluorometric assay for dopamine using a calcein blue-Fe2+ complex fluorophore.  |  Seto, D., et al. 2012. Talanta. 94: 36-43. PMID: 22608411
  3. Interfacial modification of basalt fiber filling composites with graphene oxide and polydopamine for enhanced mechanical and tribological properties.  |  Wang, J., et al. 2018. RSC Adv. 8: 12222-12231. PMID: 35539405
  4. Dopamine beta-hydroxylase: activity and inhibition in the presence of beta-substituted phenethylamines.  |  Klinman, JP. and Krueger, M. 1982. Biochemistry. 21: 67-75. PMID: 7059582

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Hydroxyphenethylamine hydrochloride, 250 mg

sc-283764
250 mg
$156.00

3-Hydroxyphenethylamine hydrochloride, 1 g

sc-283764A
1 g
$228.00

3-Hydroxyphenethylamine hydrochloride, 5 g

sc-283764B
5 g
$686.00

3-Hydroxyphenethylamine hydrochloride, 25 g

sc-283764C
25 g
$2403.00