3-Hydroxymethyl-β-carboline (CAS 65474-79-5)
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3-Hydroxymethyl- -carboline is a polyaromatic small molecule that demonstrates antagonism of the effects of benzodiazapine binding activity. 3-Hydroxymethyl-beta-carboline antagonizes the anxiolytic and anticonvulsant actions of diazepam, a property common to other 3-substitued carboline compounds including the inverse agonist Ethyl -carboline-3-carboxylate (sc-200163). The sedative effects of the benzodiazapine flurazepam are antagonized by 3-Hydroxymethyl-beta-carboline at a dose sufficiently low to have no intrinsic effect on sleep. Higher doses of 3-Hydroxymethyl- -carboline were shown to increase wakefulness and sleep latency, suggesting that an effect inverse to benzodiazapine sedation is presented by 3-Hydroxymethyl-beta-carboline activity.
3-Hydroxymethyl-β-carboline (CAS 65474-79-5) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Hydroxymethyl-β-carboline, 100 mg | sc-200165 | 100 mg | $230.00 |