Date published: 2025-10-14

1-800-457-3801

SCBT Portrait Logo
Seach Input

3-Hydroxybenzylhydrazine dihydrochloride (CAS 81012-99-9)

0.0(0)
Write a reviewAsk a question

Alternate Names:
NSD-1015
CAS Number:
81012-99-9
Purity:
97%
Molecular Weight:
211.09
Molecular Formula:
C7H10N2O•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

3-Hydroxybenzylhydrazine dihydrochloride is a white to nearly white crystalline powder. While it is water-soluble, it doesn′t dissolve in most organic solvents. The compound has demonstrated antimicrobial properties, inhibiting the growth of specific bacteria and fungi. It has also been considered for use in cosmetic products, pointing to its potential commercial value. Additionally, it acts as an enzyme inhibitor by targeting acetylcholinesterase, the enzyme responsible for breaking down acetylcholine in cholinergic synapses.


3-Hydroxybenzylhydrazine dihydrochloride (CAS 81012-99-9) References

  1. The effect of N-acetyl-L-aspartic acid dilithium salt on dopamine release and synthesis in the rat striatum in vivo.  |  Petrov, VI., et al. 2001. Eur J Pharmacol. 416: 69-73. PMID: 11282114
  2. Serotonergic depression of spinal monosynaptic transmission is mediated by 5-HT1B receptors.  |  Honda, M., et al. 2003. Eur J Pharmacol. 482: 155-61. PMID: 14660017
  3. Chromatographic assay to study the activity of multiple enzymes involved in the synthesis and metabolism of dopamine and serotonin.  |  Morgan, LD., et al. 2012. Analyst. 137: 1409-15. PMID: 22290325
  4. Central action of an inhibitor of brain dopa-decarboxylase, NSD-1015, on cyanamide-induced alcohol drinking in rats.  |  Miñano, FJ., et al. 1990. Pharmacol Biochem Behav. 35: 465-8. PMID: 2320657
  5. 5-Hydroxytryptophan, a major product of tryptophan degradation, is essential for optimal replication of human parainfluenza virus.  |  Rabbani, MAG. and Barik, S. 2017. Virology. 503: 46-51. PMID: 28113063
  6. Ebselen has lithium-like effects on central 5-HT2A receptor function.  |  Antoniadou, I., et al. 2018. Br J Pharmacol. 175: 2599-2610. PMID: 29488218
  7. L-Tyr-Induced Phosphorylation of Tyrosine Hydroxylase at Ser40: An Alternative Route for Dopamine Synthesis and Modulation of Na+/K+-ATPase in Kidney Cells.  |  Taveira-da-Silva, R., et al. 2019. Kidney Blood Press Res. 44: 1-11. PMID: 30808844
  8. Kidney dopamine D1-like receptors and angiotensin 1-7 interaction inhibits renal Na+ transporters.  |  Banday, AA., et al. 2019. Am J Physiol Renal Physiol. 317: F949-F956. PMID: 31411069
  9. Metabolism of Melatonin Synthesis-Related Indoles in the Turkey Pineal Organ and Its Modification by Monochromatic Light.  |  Martyniuk, K., et al. 2020. Int J Mol Sci. 21: PMID: 33371255
  10. Pancreatic acinar cells utilize tyrosine to synthesize L-dihydroxyphenylalanine.  |  Li, GW., et al. 2021. Exp Biol Med (Maywood). 246: 2533-2542. PMID: 34313482
  11. Modelling α-Synuclein Aggregation and Neurodegeneration with Fibril Seeds in Primary Cultures of Mouse Dopaminergic Neurons.  |  Tourville, A., et al. 2022. Cells. 11: PMID: 35626675
  12. LUHMES Cells: Phenotype Refinement and Development of an MPP+-Based Test System for Screening Antiparkinsonian Drugs.  |  Beliakov, SV., et al. 2023. Int J Mol Sci. 24: PMID: 36614176
  13. Sex-related difference in the release of dopamine into hypophysial portal blood.  |  Gudelsky, GA. and Porter, JC. 1981. Endocrinology. 109: 1394-8. PMID: 6795025
  14. Effects of delayed treatment with nafronyl oxalate on microsphere embolism-induced changes in monoamine levels of rat brain regions.  |  Takagi, N., et al. 1996. Br J Pharmacol. 118: 33-40. PMID: 8733573

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Hydroxybenzylhydrazine dihydrochloride, 100 mg

sc-266687
100 mg
$82.00