3-Hydroxy xylazine (CAS 145356-33-8)

3-Hydroxy xylazine is an active metabolite of xylazine, a compound that has gained significant attention within the realm of veterinary and biochemical research due to its unique pharmacodynamic properties. Primarily, 3-Hydroxy xylazine is noted for its modulatory effect on the alpha-2 adrenergic receptor, which plays a pivotal role in the regulation of neurotransmitter release. This interaction with the alpha-2 adrenergic receptor is of particular interest in neurochemical studies, as it provides insights into the mechanisms of sedation and analgesia at a molecular level. Furthermore, the metabolic pathway leading to 3-Hydroxy xylazine, including its formation and subsequent biological effects, offers a valuable model for understanding the pharmacokinetics and metabolism of xylazine and related compounds. As such, 3-Hydroxy xylazine serves as a critical tool in research applications, enabling scientists to dissect the complex interplay between receptor activation, neurotransmitter dynamics, and the biochemical pathways that underlie the pharmacological effects of xylazine derivatives. Its study contributes to the broader field of neuropharmacology, offering potential pathways for the development of novel research tools and models for investigating central nervous system functioning and regulation.