Molecular structure of 3-Hydroxy-4-methoxymandelic Acid, CAS Number: 3695-24-7
3-Hydroxy-4-methoxymandelic Acid (CAS 3695-24-7)
Alternate Names:
α,3-Dihydroxy-4-methoxybenzeneacetic Acid; Isovanilmandelic Acid
CAS Number:
3695-24-7
Molecular Weight:
198.17
Molecular Formula:
C9H10O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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3-Hydroxy-4-methoxymandelic Acid, also known as homovanillic acid (HVA), is a metabolite of the neurotransmitter dopamine and is found in the urine and cerebrospinal fluid of humans and other mammals. 3-Hydroxy-4-methoxymandelic Acid is an important biomarker of neurological and psychiatric disorders, such as Parkinson′s disease and schizophrenia. In scientific research, it is employed to measure the levels of dopamine in the body and to study the effects of drugs on the central nervous system. In addition, 3-Hydroxy-4-methoxymandelic Acid is used to investigate the metabolism of dopamine and its role in various physiological processes.
3-Hydroxy-4-methoxymandelic Acid (CAS 3695-24-7) References
- Application of ligand-exchange capillary electrophoresis to the chiral separation of alpha-hydroxy acids and beta-blockers. | Schmid, MG., et al. 2000. J Chromatogr A. 875: 307-14. PMID: 10839150
- Enantioseparation of hydroxy acids on easy-to-prepare continuous beds for capillary electrochromatography. | Schmid, MG., et al. 2001. Electrophoresis. 22: 2616-9. PMID: 11519967
- A glycopeptide antibiotic chiral stationary phase for the enantiomer resolution of hydroxy acid derivatives by capillary electrochromatography. | Fanali, S., et al. 2003. Electrophoresis. 24: 904-12. PMID: 12627454
- Automatic determination of urinary 4-hydroxy-3-methoxymandelic (vanillylmandelic) acid by liquid chromatography with electrochemical detection. | Ni, P., et al. 1988. J Chromatogr. 424: 255-62. PMID: 3372620
- Determination of unconjugated 3-methoxy-4-hydroxyphenylglycol by liquid chromatography for monitoring inhibition of monoamine oxidase activity in plasma. | Gupta, RN., et al. 1987. Clin Chem. 33: 2078-80. PMID: 3677382
- Determination of vanillylmandelic acid with ion-pair chromatography and fluorescence detection. | Lindgren, K. and Rodopoulos, N. 1986. Clin Chem. 32: 693-6. PMID: 3955820
- Separation of the catecholamine metabolites 4-hydroxy-3-methoxy- and 3-hydroxy-4-methoxymandelic acid by reversed-phase high performance liquid chromatography. | Stammel, W. and Thomas, H. 1985. J Chromatogr Sci. 23: 30-3. PMID: 3968195
- [Chromatographic separation and identification of 3-hydroxy,4-methoxymandelic (iso-VMa) and 4-hydroxy,3-methoxymandelic (VMA) acids in the form of their periodic oxidation derivatives: isovanillin and vanillin. Presence of 3-hydroxy,4-methoxymandelic acid in human urine]. | Mathieu, P. and Revol, L. 1969. Bull Soc Chim Biol (Paris). 51: 1347-58. PMID: 4313594
- [On the problem of the occurrence of 3-hydroxy-4-methoxymandelic acid in normal and increased catecholamine metabolism]. | von Studnitz, W. 1967. Klin Wochenschr. 45: 307-8. PMID: 5588006
- Vanillic acid, a metabolite of 4-hydroxy-3-methoxyphenylglycol and 4-hydroxy-3-methoxymandelic acid in man. | Mårdh, G. 1984. J Neurochem. 43: 522-5. PMID: 6376711
- Improved liquid-chromatographic determination of 3-methoxy-4-hydroxyphenylethyleneglycol in urine with electrochemical detection. | Shipe, JR., et al. 1984. Clin Chem. 30: 140-3. PMID: 6690122
- Determination of m-hydroxymandelic acid, m-hydroxyphenylglycol and their conjugates in human plasma using liquid chromatography with electrochemical detection. | Gumbhir, K. and Mason, WD. 1994. J Pharm Biomed Anal. 12: 943-9. PMID: 7981325
- A New Convenient Synthesis of 1-(3-Hydroxy-4-Methoxyphenyl)Ethane-1,2-Diol (iso-Mhpg) and its Enantiomers | Adrian J. Fisher and & Frank Kerrigan. 1998 -. An International Journal for Rapid Communication of Synthetic Organic Chemistry. Volume 28, Issue 16: Pages 2959-2968.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Hydroxy-4-methoxymandelic Acid, 100 mg | sc-490879 | 100 mg | $406.00 |