3-Formylchromone (CAS 17422-74-1)
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3-Formylchromone (C3CA) is a naturally occurring compound that can be found in various plant species. This particular molecule belongs to a group of compounds known as chromones, which contain a chromone ring system. Due to its diverse potential applications, 3-Formylchromone has been a subject of considerable scientific interest, prompting numerous studies exploring different aspects of its properties. Among the key areas of interest are the potential applications of 3-Formylchromone in various scientific research fields. Regarding its mechanism of action, researchers have found that 3-Formylchromone acts by effectively scavenging free radicals. 3-Formylchromone has been observed to modulate the activity of various proteins involved in cell proliferation and apoptosis. 3-Formylchromone holds significant promise as a versatile compound with potential applications in diverse scientific fields. Its manifold properties and mechanisms of action make it a fascinating subject for ongoing research.
3-Formylchromone (CAS 17422-74-1) References
- Reactions of 3-formylchromone with active methylene and methyl compounds and some subsequent reactions of the resulting condensation products. | Gasparová, R. and Lácová, M. 2005. Molecules. 10: 937-60. PMID: 18007363
- Biological activity of 3-formylchromones and related compounds. | Kawase, M., et al. 2007. In Vivo. 21: 829-34. PMID: 18019419
- Synthesis of quinolines from 3-formylchromone. | Plaskon, AS., et al. 2008. J Org Chem. 73: 6010-3. PMID: 18593188
- Relationship between structure and antioxidative properties of some 3-formylchromone derivatives. | Sersen, F., et al. 2008. Med Chem. 4: 355-7. PMID: 18673147
- Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors. | Khan, KM., et al. 2009. Bioorg Med Chem. 17: 2983-8. PMID: 19329330
- 3-Formylchromones: potential antiinflammatory agents. | Khan, KM., et al. 2010. Eur J Med Chem. 45: 4058-64. PMID: 20576329
- 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells. | Yadav, VR., et al. 2012. J Biol Chem. 287: 245-256. PMID: 22065587
- Formylchromone exhibits salubrious effects against nitrosodiethylamine mediated early hepatocellular carcinogenesis in rats. | Ilamathi, M., et al. 2014. Chem Biol Interact. 219: 175-83. PMID: 24954034
- 3-Formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating STAT3 signaling through the induction of PIAS3. | Ko, JH., et al. 2016. Immunopharmacol Immunotoxicol. 38: 334-43. PMID: 27324722
- 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells. | Yadav, VR., et al. 2016. J Biol Chem. 291: 16926. PMID: 27496967
- Sulfonyl hydrazones derived from 3-formylchromone as non-selective inhibitors of MAO-A and MAO-B: Synthesis, molecular modelling and in-silico ADME evaluation. | Abid, SMA., et al. 2017. Bioorg Chem. 75: 291-302. PMID: 29065322
- Synthesis, Spectroscopic Analysis and Assessment of the Biological Activity of New Hydrazine and Hydrazide Derivatives of 3-Formylchromone. | Słomiak, K., et al. 2018. Molecules. 23: PMID: 30126150
- One Pot and Metal-Free Approach to 3-(2-Hydroxybenzoyl)-1-aza-anthraquinones. | Yuan, J., et al. 2019. Molecules. 24: PMID: 31434258
- Synthesis of heterocyclic analogs of isoflavone and homoisoflavone based on 3-formylchromone. | Shatokhin, SS., et al. 2021. Russ Chem Bull. 70: 1011-1045. PMID: 34305378
- NiII and CoII binary and ternary complexes of 3-formylchromone: spectroscopic characterization, antimicrobial activities, docking and modeling studies. | Nabil, N., et al. 2022. RSC Adv. 12: 29939-29958. PMID: 36321099
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Formylchromone, 5 g | sc-254484 | 5 g | $34.00 |