Date published: 2026-6-4

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3-Fluoropropyl trifluoromethanesulphonate (CAS 180597-96-0)

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Alternate Names:
3-Fluoroprop-1-yl trifluoromethanesulphonate; 3-Fluoroprop-1-yl triflate
CAS Number:
180597-96-0
Molecular Weight:
210.15
Molecular Formula:
C4H6F4O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Fluoropropyl trifluoromethanesulphonate is a chemical compound that garners attention in the field of organic chemistry, particularly for its role as a reagent in the introduction of fluorinated alkyl groups into organic molecules. Its application is pivotal in studies focusing on the incorporation of fluorine into certain compounds to alter their biological activity, stability, and membrane permeability. The compound acts as an alkylating agent, providing a pathway for carbon-fluorine bond formation, which is a topic of considerable interest due to the unique properties imparted by fluorination. In addition, 3-Fluoropropyl trifluoromethanesulphonate is used in material science, where the incorporation of fluorinated groups can lead to materials with enhanced chemical resistance and lower surface energies. Its role in synthetic methodologies is also studied in the context of developing more efficient and selective fluorination reactions.


3-Fluoropropyl trifluoromethanesulphonate (CAS 180597-96-0) References

  1. Synthesis and analysis of 4-(3-fluoropropyl)-glutamic acid stereoisomers to determine the stereochemical purity of (4S)-4-(3-[18F]fluoropropyl)-L-glutamic acid ([18F]FSPG) for clinical use.  |  Shih, KT., et al. 2020. PLoS One. 15: e0243831. PMID: 33315962
  2. A Reactivity-Based 18F-Labeled Probe for PET Imaging of Oxidative Stress in Chemotherapy-Induced Cardiotoxicity.  |  Mota, F., et al. 2022. Mol Pharm. 19: 18-25. PMID: 34846906

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Fluoropropyl trifluoromethanesulphonate, 1 g

sc-260987
1 g
$201.00

3-Fluoropropyl trifluoromethanesulphonate, 5 g

sc-260987A
5 g
$624.00