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Triacsin C Solution in DMSO was originally isolated from a Streptomyces aureofaciens culture. The compound is an inhibitor of long fatty acid acyl-CoA synthetase (ACSL) in intact cells and the nonspecific ACSL in cell sonicates (IC50=3.6-8.7 muM). Triacsin C Solution in DMSO may act to inhibit de novo synthesis of triacylglycerol, diacylglycerol, cholesterol esters, and phospholipids. The inhibitory effect of Triacsin C prevents degranulation by human neutrophils through superoxide anion generation inhibition, thus inhibiting neutrophil activity. Triacsin C Solution in DMSO has been classified as a hypotensive vasodilator which may act by increasing methacholine-induced NO synthesis. The compound has also been reported to inhibit beta-cells by abolishing L-type Ca2+ CP (L-type Ca2+) channel modulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Ethoxy-N-[2-(2-isopropylphenoxy)ethyl]aniline, 500 mg | sc-312936 | 500 mg | $284.00 |