C-12 NBD Cholesterol is a fluorescently-tagged cholesterol with the hydrophilic NBD fluorophore attached to the hydrophilic end of cholesterol, separated by a 12-carbon spacer. This allows the cholesterol to orient in membrane bilayers while the fluorescent tag is presented outside the bilayer. Fluorescently-tagged lipids have been used to study their interactions with proteins, utilization by cells and liposomes, and development of assays for lipid metabolism.
1. Kumagai, K., et al. 2005. J. Biol. Chem. 280: 6488-6495. PMID: 15596449 2. Luo, M., et al. 2003. Proc. Natl. Acad. Sci. U.S.A. 100: 12165-12170. PMID: 14530386 3. Tani, M., et al. 1999. J. Biochem. 125: 746-749. PMID: 10101288
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For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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sc-220866 is in stock?
Asked by: bobxie
Thank you for your question. For accurate availability, shipping and pricing information regarding our chemical products, please contact Customer Service.
Answered by: Tech Service
Date published: 2020-01-08
I have received this compound (3-dodecanoyl-NBD Cholesterol 0.5 mg; sc-220866) but there is no information about the solvent and the concentration. Can anyone give me these data? Thank you in advance
Asked by: Jesus1
Thank you for your question. This comes supplied in ethanol. To change solvent, you can evaporate the ethanol under a stream of nitrogen and immediately add solvent of choice.
Solubility is 0.25 mg mg/mlDMSO, 1 mg/ml DMF.
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