3-dodecanoyl-NBD Cholesterol CAS: 1246303-05-8
MF: C45H70N4O5
MW: 747.1
A fluorescently-tagged cholesterol.

3-dodecanoyl-NBD Cholesterol (CAS 1246303-05-8)

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Application: 3-dodecanoyl-NBD Cholesterol is a fluorescently-tagged cholesterol
CAS Number: 1246303-05-8
Purity: ≥98%
Molecular Weight: 747.1
Molecular Formula: C45H70N4O5
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

C-12 NBD Cholesterol is a fluorescently-tagged cholesterol with the hydrophilic NBD fluorophore attached to the hydrophilic end of cholesterol, separated by a 12-carbon spacer. This allows the cholesterol to orient in membrane bilayers while the fluorescent tag is presented outside the bilayer. Fluorescently-tagged lipids have been used to study their interactions with proteins, utilization by cells and liposomes, and development of assays for lipid metabolism.


References

1. Kumagai, K., et al. 2005. J. Biol. Chem. 280: 6488-6495. PMID: 15596449
2. Luo, M., et al. 2003. Proc. Natl. Acad. Sci. U.S.A. 100: 12165-12170. PMID: 14530386
3. Tani, M., et al. 1999. J. Biochem. 125: 746-749. PMID: 10101288

Physical State :
Liquid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
UN 1170, Class 3, Packing group II
SMILES :
[H]N(C1=CC=C([N+]([O-])=O)C2=NON=C12)CCCCCCCCCCCCC(O[[email protected]](C3)CC[[email protected]@]4(C)C3=CC[[email protected]]5([H])[[email protected]]4([H])CC[[email protected]@]6(C)[[email protected]@]5([H])CC[[email protected]]6([H])[[email protected]@](C)([H])CCCC(C)C)=O

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Certificate of Analysis

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sc-220866 is in stock?

Asked by: bobxie
Thank you for your question. For accurate availability, shipping and pricing information regarding our chemical products, please contact Customer Service.
Answered by: Tech Service
Date published: 2020-01-08

I have received this compound (3-dodecanoyl-NBD Cholesterol 0.5 mg; sc-220866) but there is no information about the solvent and the concentration. Can anyone give me these data? Thank you in advance

Asked by: Jesus1
Thank you for your question. This comes supplied in ethanol. To change solvent, you can evaporate the ethanol under a stream of nitrogen and immediately add solvent of choice. Solubility is 0.25 mg mg/mlDMSO, 1 mg/ml DMF.
Answered by: Tech Service
Date published: 2019-03-01
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