Date published: 2025-11-2

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3-dodecanoyl-NBD Cholesterol (CAS 1246303-05-8)

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Application:
3-dodecanoyl-NBD Cholesterol is a fluorescently-tagged cholesterol
CAS Number:
1246303-05-8
Purity:
≥98%
Molecular Weight:
747.1
Molecular Formula:
C45H70N4O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-dodecanoyl-NBD Cholesterol is a fluorescently-tagged cholesterol with the hydrophilic NBD fluorophore attached to the hydrophilic end of cholesterol, separated by a 12-carbon spacer. This allows the cholesterol to orient in membrane bilayers while the fluorescent tag is presented outside the bilayer. Fluorescently-tagged lipids have been used to study their interactions with proteins, utilization by cells and liposomes, and development of assays for lipid metabolism.


3-dodecanoyl-NBD Cholesterol (CAS 1246303-05-8) References

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  3. Kaempferol suppresses lipid accumulation in macrophages through the downregulation of cluster of differentiation 36 and the upregulation of scavenger receptor class B type I and ATP-binding cassette transporters A1 and G1.  |  Li, XY., et al. 2013. Int J Mol Med. 31: 331-8. PMID: 23232972
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  7. IRAK regulates macrophage foam cell formation by modulating genes involved in cholesterol uptake and efflux.  |  Rana, M., et al. 2016. Bioessays. 38: 591-604. PMID: 27270491
  8. Coral cell separation and isolation by fluorescence-activated cell sorting (FACS).  |  Rosental, B., et al. 2017. BMC Cell Biol. 18: 30. PMID: 28851289
  9. Andrographolide Inhibits Oxidized LDL-Induced Cholesterol Accumulation and Foam Cell Formation in Macrophages.  |  Lin, HC., et al. 2018. Am J Chin Med. 46: 87-106. PMID: 29298513
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  14. Factor VIIa Regulates the Level of Cell-Surface Tissue Factor through Separate but Cooperative Mechanisms.  |  Madkhali, Y., et al. 2021. Cancers (Basel). 13: PMID: 34359618

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-dodecanoyl-NBD Cholesterol, 500 µg

sc-220866
500 µg
$139.00

3-dodecanoyl-NBD Cholesterol, 1 mg

sc-220866A
1 mg
$264.00