Molecular structure of 3-Desacetyl cefotaxime, CAS Number: 66340-28-1
3-Desacetyl cefotaxime (CAS 66340-28-1)
Alternate Names:
3-Desacetyl cefotaxime also known as Deacetylcefotaxime
Application:
3-Desacetyl cefotaxime is a cefotaxime sodium salt impurity and can be used as a broad-spectrum cephalosporin antibiotic
CAS Number:
66340-28-1
Molecular Weight:
413.43
Molecular Formula:
C14H15N5O6S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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3-Desacetyl Cefotaxime is a compound used in research related to beta-lactam antibiotics. While 3-Desacetyl Cefotaxime itself is not an antibiotic, it is a significant metabolite of cefotaxime, a third-generation cephalosporin. Studies involving this compound often focus on its kinetics and the metabolic pathways of cefotaxime. Research typically aims to understand the degradation process and the activity of beta-lactamase enzymes that might inactivate the parent compound. Additionally, 3-Desacetyl Cefotaxime is used as a reference standard in analytical methods, such as high-performance liquid chromatography (HPLC), to accurately measure levels of cefotaxime and its metabolites in various biological matrices.
3-Desacetyl cefotaxime (CAS 66340-28-1) References
- Application of solid phase microextraction followed by liquid chromatography-mass spectrometry in the determination of antibiotic drugs and their metabolites in human whole blood and tissue samples. | Szultka-Mlynska, M., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1086: 153-165. PMID: 29677683
- Study of chromatographic behavior of antibiotic drugs and their metabolites based on quantitative structure-retention relationships with the use of HPLC-DAD. | Walczak-Skierska, J., et al. 2020. J Pharm Biomed Anal. 184: 113187. PMID: 32109708
- Determination and Identification of Antibiotic Drugs and Bacterial Strains in Biological Samples. | Pauter, K., et al. 2020. Molecules. 25: PMID: 32486359
- Antibiotics and Non-Targeted Metabolite Residues Detection as a Comprehensive Approach toward Food Safety in Raw Milk. | Chiesa, LM., et al. 2021. Foods. 10: PMID: 33800733
- Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. | Guerra Valero, YC., et al. 2021. Anal Bioanal Chem. 413: 4483-4491. PMID: 34041575
- Molecularly Imprinted Polymers as Solid-Phase Microextraction Fibers for the Isolation of Selected Antibiotics from Human Plasma. | Szultka-Młyńska, M., et al. 2021. Materials (Basel). 14: PMID: 34500975
- CE-DAD-MS/MS in the simultaneous determination and identification of selected antibiotic drugs and their metabolites in human urine samples. | Pauter, K., et al. 2022. Electrophoresis. 43: 978-989. PMID: 34624141
- Degradation of Penicillinic Antibiotics and β-Lactamase Enzymatic Catalysis in a Biomimetic Zn-Based Metal-Organic Framework. | Escamilla, P., et al. 2023. Chemistry. 29: e202301325. PMID: 37279057
- Degradation of Penicillinic Antibiotics and β-Lactamase Enzymatic Catalysis in a Biomimetic Zn-Based Metal-Organic Framework. | Escamilla, P., et al. 2023. Chemistry. 29: e202302315. PMID: 37697892
- Development and Validation of a Capillary Zone Electrophoresis-Tandem Mass Spectrometry Method for Simultaneous Quantification of Eight β-Lactam Antibiotics and Two β-Lactamase Inhibitors in Plasma Samples. | Cizmarova, I., et al. 2024. Pharmaceuticals (Basel). 17: PMID: 38675486
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Desacetyl cefotaxime, 5 mg | sc-471322 | 5 mg | $607.00 | |||
3-Desacetyl cefotaxime, 25 mg | sc-471322A | 25 mg | $2289.00 |