Date published: 2025-10-16

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3-Deoxy-D-glucose (CAS 2490-91-7)

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Application:
3-Deoxy-D-glucose is has been used for the production of deoxy adenines
CAS Number:
2490-91-7
Purity:
≥98%
Molecular Weight:
164.16
Molecular Formula:
C6H12O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

3-Deoxy-D-glucose has been used for the production of deoxy adenines. 3-Deoxy-D-glucose is a naturally occurring compound present in several plants and fungi, and is categorized as an aldehyde. Numerous studies have revealed that this compound possesses anti-inflammatory, antioxidant, and anti-cancer properties. It can be synthesized through the reaction between 4-hydroxy-2-methylpentanal and sodium hydroxide.


3-Deoxy-D-glucose (CAS 2490-91-7) References

  1. A heat-sensitive TRP channel expressed in keratinocytes.  |  Peier, AM., et al. 2002. Science. 296: 2046-9. PMID: 12016205
  2. Mutational analysis of the hexose transporter of Plasmodium falciparum and development of a three-dimensional model.  |  Manning, SK., et al. 2002. J Biol Chem. 277: 30942-9. PMID: 12042321
  3. The phosphate esters of mammalian skin maintained on glucose and various deoxyglucoses.  |  BROOKS, SA., et al. 1959. Biochem J. 73: 566-72. PMID: 13804794
  4. Purification and biochemical characterisation of a membrane-bound alpha-glucosidase from the parasite Entamoeba histolytica.  |  Bravo-Torres, JC., et al. 2004. Int J Parasitol. 34: 455-62. PMID: 15013735
  5. Substrate specificity of sugar transport by rabbit SGLT1: single-molecule atomic force microscopy versus transport studies.  |  Puntheeranurak, T., et al. 2007. Biochemistry. 46: 2797-804. PMID: 17302432
  6. 3-Deoxy-beta-D-ribo-hexopyranose (3-deoxy-beta-D-glucopyranose).  |  Zhang, W., et al. 2007. Acta Crystallogr C. 63: o578-81. PMID: 17917226
  7. The interaction of 3-deoxy-3-fluoro-D-glucose with the hexose-transport system of the human erythrocyte.  |  Riley, GJ. and Taylor, NF. 1973. Biochem J. 135: 773-7. PMID: 4778273
  8. Structural requirements of D-glucose for its binding to isolated human erythrocyte membranes.  |  Kahlenberg, A. and Dolansky, D. 1972. Can J Biochem. 50: 638-43. PMID: 5042872
  9. Structural requirements for active intestinal transport. Spatial and bonding requirements at C-3 of the sugar.  |  Barnett, JE., et al. 1969. Biochem J. 114: 569-73. PMID: 5820643
  10. Synthesis of 3'-deoxynucleosides. II. Synthesis of 9-(3-deoxyaldofuranosyl) adenines derived from 3-deoxy-D-glucose.  |  Murray, DH. and Prokop, J. 1965. J Pharm Sci. 54: 1468-73. PMID: 5883218
  11. Hydrogen bonding requirements for the insulin-sensitive sugar transport system of rat adipocytes.  |  Rees, WD. and Holman, GD. 1981. Biochim Biophys Acta. 646: 251-60. PMID: 7028115
  12. The uptake of 3-deoxy-3-fluoro-D-glucose by synaptosomes from rat brain cortex.  |  Halton, DM., et al. 1980. J Neurosci Res. 5: 241-52. PMID: 7401201
  13. Effect of 2-deoxy-D-glucose on Herpetomonas samuelpessoai.  |  Bunn, MM., et al. 1977. Z Parasitenkd. 52: 245-56. PMID: 906630

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Deoxy-D-glucose, 25 mg

sc-220862
25 mg
$262.00