Date published: 2026-4-30

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3-Chloro-4-methoxybenzoic acid (CAS 37908-96-6)

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Alternate Names:
3-Chloro-p-anisic acid
CAS Number:
37908-96-6
Molecular Weight:
186.59
Molecular Formula:
C8H7ClO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Chloro-4-methoxybenzoic acid has various cientific research applications. It is used as a key building block essential for synthesizing a range of materials and dyes. It acts as a versatile reagent, facilitating the synthesis of diverse compounds, including 3-chloro-4-methoxybenzamide and 3-chloro-4-methoxybenzoic anhydride. 3-Chloro-4-methoxybenzoic acid has been used in synthesis of polymers and other essential materials.


3-Chloro-4-methoxybenzoic acid (CAS 37908-96-6) References

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  2. Significant biogenesis of chlorinated aromatics by fungi in natural environments.  |  de Jong, E., et al. 1994. Appl Environ Microbiol. 60: 264-70. PMID: 16349156
  3. Transformation of avobenzone in conditions of aquatic chlorination and UV-irradiation.  |  Trebše, P., et al. 2016. Water Res. 101: 95-102. PMID: 27258620
  4. Stability and removal of selected avobenzone's chlorination products.  |  Wang, C., et al. 2017. Chemosphere. 182: 238-244. PMID: 28500968
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  6. Discovery of a potent p38α/MAPK14 kinase inhibitor: Synthesis, in vitro/in vivo biological evaluation, and docking studies.  |  El-Gamal, MI., et al. 2019. Eur J Med Chem. 183: 111684. PMID: 31520926
  7. Biological Evaluation and In Silico Study of Benzoic Acid Derivatives from Bjerkandera adusta Targeting Proteostasis Network Modules.  |  Georgousaki, K., et al. 2020. Molecules. 25: PMID: 32033190
  8. Synthesis, biological evaluation, and docking studies of new pyrazole-based thiourea and sulfonamide derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase.  |  Ullah, S., et al. 2020. Bioorg Chem. 99: 103783. PMID: 32224334
  9. Degradation of methoxylated benzoic acids by a Nocardia from a lignin-rich environment: significance to lignin degradation and effect of chloro substituents.  |  Crawford, RL., et al. 1973. Appl Microbiol. 26: 176-84. PMID: 4743871
  10. Determination of metabolites of 3-chloro-4-benzyloxyphenylacetic acid (benzofenac) by GC/MS method.  |  Koruna, I., et al. 1984. Biomed Mass Spectrom. 11: 121-6. PMID: 6722283
  11. Diarylspiro[2.4]heptenes as orally active, highly selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationships.  |  Huang, HC., et al. 1996. J Med Chem. 39: 253-66. PMID: 8568815
  12. Crystal structures, spectroscopic, and thermal properties of Dysprosium (III) and Europium (III) complexes with 3-chloro-4-methoxybenzoic and 1,10-phenanthroline  |  , et al. 2015. Journal of Thermal Analysis and Calorimetry. 119: 1803–1810.
  13. Crystal structure, thermochemical and fluorescent properties of two novel binuclear lanthanide complexes with 3-chloro-4-methoxybenzoic acid and 5,5′-dimethy-2,2′-bipyridine  |  W Xiao-Hui, R Ning, Z Jian-Jun. 2019. The Journal of Chemical Thermodynamics. 476-483: 476-483.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Chloro-4-methoxybenzoic acid, 5 g

sc-231598
5 g
$67.00