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Iberotoxin is a highly selective and potent blocker of the MaxiK (high conductance Ca2+ activated K+ channels) that does not affect other types of voltage-dependent K+ channels. Because of iberiotoxin′s strong ability to block Ca2+ activated K+ channels, in mammalian motor nerve terminals the compound can induce dihydropyridine sensitive release of ACh. In rat organotypic dorsal striatal slices iberiotoxin and margatoxin (sc-358754) were both observed to induce production of c-fos like mRNA and protein. Iberiotoxin is an inhibitor of MaxiKalpha.
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Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Chloro-4-(difluoromethoxy)aniline, 500 mg | sc-312766 | 500 mg | $180.00 |