Date published: 2025-12-10

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3-Chloro-2-fluoroprop-1-ene (CAS 6186-91-0)

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Alternate Names:
1-Chloro-2-fluoro-2-propene
CAS Number:
6186-91-0
Molecular Weight:
94.52
Molecular Formula:
C3H4ClF
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Chloro-2-fluoroprop-1-ene (3-CFPE) is a versatile organic compound widely utilized in the chemical and pharmaceutical industries for various purposes. It serves as a intermediate in the synthesis of numerous pharmaceuticals, agrochemicals, and other organic compounds. Additionally, it finds application in the production of fluoropolymers and other fluorinated materials. In scientific research, 3-Chloro-2-fluoroprop-1-ene holds a broad range of uses. It acts as a reagent for synthesizing new compounds, functions as a catalyst in organic reactions, and serves as a solvent in various chemical processes. Moreover, it acts as a stabilizer for enzymes, participates in gas-phase and liquid-phase reactions, and contributes to the production of fluoropolymers and other fluorinated materials. The mechanism of action of 3-Chloro-2-fluoroprop-1-ene is centered around its ability to react with other chemical compounds, leading to the formation of stable bonds. It serves as a catalyst in organic reactions, enabling the transformation of reactants into desired products. Furthermore, it exhibits inhibitory effects on the growth of certain bacteria, fungi, and viruses in vitro. Additionally, it displays anti-inflammatory and anti-tumor properties in vitro.


3-Chloro-2-fluoroprop-1-ene (CAS 6186-91-0) References

  1. Correction: Block et al. Fluorinated Analogs of Organosulfur Compounds from Garlic (Allium sativum): Synthesis, Chemistry and Anti-Angiogenesis and Antithrombotic Studies. Molecules 2017, 22, 2081.  |  Block, E., et al. 2023. Molecules. 28: PMID: 36771183
  2. A practical and straightforward access to fluorinated homoallylic alcohols in aqueous media  |  G Lemonnier, T Poisson, S Couve-Bonnaire. 2013. Tetrahedron Letters. 54: 2821-2824.
  3. Efficient access to fluorinated homoallylic alcohols through an indium promoted fluoroallylation reaction  |  G Lemonnier, N Van Hijfte, M Sebban, T Poisson. 2014. Tetrahedron. 70: 3123-3133.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Chloro-2-fluoroprop-1-ene, 5 g

sc-310806
5 g
$446.00