Date published: 2025-9-27

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3-Carene (CAS 13466-78-9)

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Alternate Names:
3,7,7-Trimethylbicyclo[4.1.0]hept-3-ene
Application:
3-Carene is a bicyclic monoterpene turpentine constituent
CAS Number:
13466-78-9
Purity:
≥90%
Molecular Weight:
136.23
Molecular Formula:
C10H16
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Carene has a bicyclic monoterpene structure and is found as a terpentine constituent. 3-Carene, a bicyclic monoterpene present in numerous essential oils, holds great significance across various industries like food and cosmetics. Being a natural compound, it exhibits an impressive array of biological activities, including antibacterial, antifungal, and antiviral properties, along with beneficial effects. Though the exact mechanism of action remains partially elusive, researchers speculate that it involves multiple pathways. For instance, 3-Carene has been found to hinder the activity of specific enzymes responsible for cell signaling, such as cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). Moreover, it can activate the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, a vital regulator of antioxidant enzymes. 3-Carene′s remarkable attributes and potential applications in various industries make it a fascinating subject of ongoing research, paving the way for a deeper understanding of its properties.


3-Carene (CAS 13466-78-9) References

  1. Isolation and functional characterization of a methyl jasmonate-responsive 3-carene synthase from Lavandula x intermedia.  |  Adal, AM., et al. 2017. Plant Mol Biol. 93: 641-657. PMID: 28258552
  2. Ozonolysis of 3-carene in the atmosphere. Formation mechanism of hydroxyl radical and secondary ozonides.  |  Wang, L., et al. 2019. Phys Chem Chem Phys. 21: 8081-8091. PMID: 30932098
  3. Antimicrobial Activity and Proposed Action Mechanism of 3-Carene against Brochothrix thermosphacta and Pseudomonas fluorescens.  |  Shu, H., et al. 2019. Molecules. 24: PMID: 31489899
  4. 3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABAA-benzodiazepine Receptors.  |  Woo, J., et al. 2019. Exp Neurobiol. 28: 593-601. PMID: 31698551
  5. CcOBP2 plays a crucial role in 3-carene olfactory response of the parasitoid wasp Chouioia cunea.  |  Pan, L., et al. 2020. Insect Biochem Mol Biol. 117: 103286. PMID: 31760134
  6. Metabolomics study on revealing the inhibition and metabolic dysregulation in Pseudomonas fluorescens induced by 3-carene.  |  Shu, H., et al. 2020. Food Chem. 329: 127220. PMID: 32516715
  7. Evaluation of the Insecticidal Activities of α-Pinene and 3-Carene on Sitophilus zeamais Motschulsky (Coleoptera: Curculionidae).  |  Langsi, JD., et al. 2020. Insects. 11: PMID: 32824401
  8. Role of 3-Carene in Host Location and Colonization by Dendroctonus pseudotsugae (Coleoptera: Curculionidae).  |  Ross, DW., et al. 2022. Environ Entomol. 51: 190-195. PMID: 34698824
  9. Antibacterial Mechanism of 3-Carene against the Meat Spoilage Bacterium Pseudomonas lundensis and Its Application in Pork during Refrigerated Storage.  |  Tang, Z., et al. 2021. Foods. 11: PMID: 35010218
  10. Synthesis of 3-carene-derived nanocellulose/1,3,4-thiadiazole-amide complexes with antifungal activity for plant protection.  |  Zou, R., et al. 2022. Pest Manag Sci. 78: 3277-3286. PMID: 35484724
  11. Unraveling the antibacterial mechanism of 3-carene against Pseudomonas fragi by integrated proteomics and metabolomics analyses and its application in pork.  |  Tang, Z., et al. 2022. Int J Food Microbiol. 379: 109846. PMID: 35908494
  12. Synthesis, Antifungal Activity, and Molecular Docking Study of Novel 3-Carene-Derived 4-Substituted Phenyl-1,2,4-Triazolinthiones Bearing gem-Dimethylcyclopropane Moiety.  |  Li, B., et al. 2022. Chem Biodivers. 19: e202200726. PMID: 36121765
  13. Effects of low concentrations of 3-carene on alveolar macrophages in vitro.  |  Johansson, A. and Lundborg, M. 1997. Toxicology. 120: 99-104. PMID: 9184196

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Carene, 25 ml

sc-225996
25 ml
$29.00