Date published: 2026-4-2

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3-Butenenitrile (CAS 109-75-1)

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Alternate Names:
Allyl cyanide, Vinylacetonitrile
Application:
3-Butenenitrile is an antimicrobial
CAS Number:
109-75-1
Purity:
>90%
Molecular Weight:
67.09
Molecular Formula:
C4H5N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Butenenitrile, also known as allyl cyanide, has garnered significant interest in scientific research due to its diverse applications and versatile chemical reactivity. One area of focus lies in its role as a precursor in organic synthesis, where it serves as a valuable building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and fine chemicals. Chemists have explored its use in the synthesis of heterocyclic compounds, such as pyrroles and pyridines, which are important structural motifs found in many biologically active molecules. Additionally, 3-butenenitrile has been employed in the development of novel materials, including polymers and coordination complexes, owing to its ability to participate in various chemical reactions, such as nucleophilic addition and transition metal-catalyzed transformations. Research efforts have also investigated its potential as a starting material for the preparation of functionalized organic molecules with tailored properties for applications in materials science, catalysis, and medicinal chemistry. Furthermore, studies continue to explore new synthetic methodologies and reaction pathways involving 3-butenenitrile, aiming to expand its utility and contribute to advancements in organic chemistry and related fields.


3-Butenenitrile (CAS 109-75-1) References

  1. Electrophysiological deficiency in peripheral nerve induced by treatment for 12 weeks with 2-butenenitrile, 3-butenenitrile, cis-2-pentenenitrile and 3,3-iminodipropionitrile in rats.  |  Gagnaire, F. and Marignac, B. 1999. Pharmacol Toxicol. 84: 247-54. PMID: 10401725
  2. The ototoxic effects induced in rats by treatment for 12 weeks with 2-butenenitrile, 3-butenenitrile and cis-2-pentenenitrile.  |  Gagnaire, F., et al. 2001. Pharmacol Toxicol. 88: 126-34. PMID: 11245407
  3. Competition and selectivity in the reaction of nitriles on ge(100)-2x1.  |  Filler, MA., et al. 2003. J Am Chem Soc. 125: 4928-36. PMID: 12696912
  4. Surface reactions of 3-butenenitrile on the Si(001)-2 x 1 surface at room temperature.  |  Rangan, S., et al. 2005. J Phys Chem B. 109: 12899-908. PMID: 16852601
  5. The Role of a Glucosinolate-Derived Nitrile in Plant Immune Responses.  |  Ting, HM., et al. 2020. Front Plant Sci. 11: 257. PMID: 32211010
  6. Investigating the cause of Brassica-associated liver disease (BALD) in cattle: Progoitrin-derived nitrile toxicosis in rats.  |  Matthews, ZM., et al. 2020. Toxicon X. 5: 100021. PMID: 32550577
  7. Key Odorant Differences in Fragrant Brassica napus and Brassica juncea Oils Revealed by Gas Chromatography-Olfactometry, Odor Activity Values, and Aroma Recombination.  |  Jia, X., et al. 2020. J Agric Food Chem. 68: 14950-14960. PMID: 33227196
  8. Comparative Analysis of Traditional and Modern Fermentation for Xuecai and Correlations Between Volatile Flavor Compounds and Bacterial Community.  |  Zhang, J., et al. 2021. Front Microbiol. 12: 631054. PMID: 33995294
  9. Biodegradation of nitriles derived from glucosinolates in rapeseed meal by BnNIT2: a nitrilase from Brassica napus with wide substrate specificity.  |  Zhang, H., et al. 2022. Appl Microbiol Biotechnol. 106: 2445-2454. PMID: 35262786
  10. Identification and biotransformation analysis of volatile markers during the early stage of Salmonella contamination in chicken.  |  Wang, Y., et al. 2024. Food Chem. 431: 137130. PMID: 37591139

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Butenenitrile, 25 g

sc-238508
25 g
$66.00

3-Butenenitrile, 100 g

sc-238508A
100 g
$205.00