3-Bromopyruvic acid | CAS 1113-59-3 | SCBT - Santa Cruz Biotechnology
3-Bromopyruvic acid CAS: 1113-59-3
MF: C3H3BrO3
MW: 166.96

3-Bromopyruvic acid (CAS 1113-59-3)

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Alternate Names: 3-Bromopyruvic acid is also known as 3-Bromo-2-oxopropionic acid.
Application: 3-Bromopyruvic acid is a cross-linker between nucleic acids and proteins, and is also an affinity label for cysteine residues.
CAS Number: 1113-59-3
Purity: ≥97%
Molecular Weight: 166.96
Molecular Formula: C3H3BrO3
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).

3-Bromopyruvic acid is a brominated derivative of pyruvic acid (sc-208191), which inhibits HXK II (hexokinase II) in cancer cells. As a result of this inhibition the cells are unable to metabolize glucose into ATP directly. Studies conducted on MCF-7 (sc-2206) breast cancer cells show that 3-Bromopyruvic acid hydrate reduces the expression of Bcl-2, c-Myc and mutant p53, which are involved in the cell death signal transduction pathway. Alternate studies indicate that 3-Bromopyruvic acid hydrate is a very selective antibiotic, inhibiting the growth of certain yeasts.


1. ZYGMUNT, W.A. and MARTIN, T.A. 1964. J Pharm Sci. 53 : 1420-1421. PMID: 14253613
2. Liu, X.H. et al. 2009. Chin. Med. J. 122(14): 1681-1685. PMID: 19719971

Appearance :
Physical State :
Solubility :
Soluble in water (100 mg/ml), DMSO, ethyl acetate, and water.
Storage :
Store at 4° C
Melting Point :
77-82° C
Boiling Point :
~223.4° C at 760 mmHg (Predicted)
Density :
~2.0 g/cm3 (Predicted)
Refractive Index :
n20D 1.52 (Predicted)
pK Values :
pKa: 1.84 (Predicted)
WGK Germany :
PubChem CID :
MDL Number :
EC Number :
Beilstein Registry :

Download SDS (MSDS)

Certificate of Analysis

SAMPLE Certificate of Analysis (COA)

Catalog Number:sc-260854
Lot Number:SAMPLE
Product Name:3-Bromopyruvic acid hydrate
Molecular Formula:C3H3BrO3•H2O
Molecular Weight:184.97
AppearanceLight beige powder
Purity (Acid Titration)98.3%

3-Bromopyruvic acid (CAS 1113-59-3)  Product Citations

See how others have used 3-Bromopyruvic acid (CAS 1113-59-3). Click on the entry to view the PubMed entry .

Citations 1 to 7 of 7 total

PMID: 32615946 |  | BMC Cancer. 617.

PMID: 31669882 |  | Pharmacol Rep. 1184-1189.

Citations 1 to 7 of 7 total

Is 3-bromopyruvate soluble in saline solution?

Asked by: Abha
Thank you for your question. We found that this is soluble in isotonic saline, but were not able to find a recommended concentration.
Answered by: Technical Support
Date published: 2019-09-11

I want 3-bromopyruvic acid for human clinical trials soon, therefore I need cGMP certification for this product. If I want to order 40kg of this in cGMP level, what's the quotations?

Asked by: bkim019
We cannot provide chemicals regulated as ISO certified and GMP compliant. Our chemicals are for in vitro research use only. Not intended for diagnostic of therapeutic use.
Answered by: Technical Support
Date published: 2021-09-08
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