Date published: 2026-4-29

1-800-457-3801

SCBT Portrait Logo
Seach Input

3-Bromo-1-butyne (CAS 18668-72-9)

0.0(0)
Write a reviewAsk a question

Application:
3-Bromo-1-butyne is a building block for synthesis
CAS Number:
18668-72-9
Purity:
≥90%
Molecular Weight:
132.99
Molecular Formula:
C4H5Br
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

3-Bromo-1-butyne is used in biochemistry. 3-Bromo-1-butyne is used in the synthesis of complex organic molecules, particularly in the field of medicinal chemistry. Its unique structure and reactivity allow for the introduction of functional groups into organic molecules. 3-Bromo-1-butyne is a useful building block in the preparation of bioconjugates, which are used for studying protein-protein interactions and other biological processes.


3-Bromo-1-butyne (CAS 18668-72-9) References

  1. W(CO)5(L)-catalyzed endo-selective cyclization of allenyl silyl enol ethers: an efficient method for the cyclopentene annulation onto alpha,beta-unsaturated ketones.  |  Miura, T., et al. 2003. Org Lett. 5: 1725-8. PMID: 12735762
  2. Studies on acetylenic compounds. XXVI. Ring closure. (6). New synthetic method of heterocyclic compounds from alpha-substituted acetylenic compounds.  |  YURA, Y. 1962. Chem Pharm Bull (Tokyo). 10: 1094-8. PMID: 14002923
  3. Experimental and theoretical studies of the propargyl-allenylindium system.  |  Miao, W., et al. 2004. J Am Chem Soc. 126: 13326-34. PMID: 15479088
  4. In situ generation of vinyl allenes and its applications to one-pot assembly of cyclohexene, cyclooctadiene, 3,7-nonadienone, and bicyclo[6.4.0]dodecene derivatives with palladium-catalyzed multicomponent reactions.  |  Lee, PH., et al. 2006. J Am Chem Soc. 128: 1139-46. PMID: 16433529
  5. Preparation of organoaluminum reagents from propargylic bromides and aluminum activated by PbCl2 and their regio- and diastereoselective addition to carbonyl derivatives.  |  Guo, LN., et al. 2010. Chemistry. 16: 9829-34. PMID: 20572180
  6. Imaging breakdown diagrams for bromobutyne isomers with photoelectron-photoion coincidence.  |  Bodi, A. and Hemberger, P. 2014. Phys Chem Chem Phys. 16: 505-15. PMID: 24108175
  7. Discovery of highly potent DPP-4 inhibitors by hybrid compound design based on linagliptin and alogliptin.  |  Lai, ZW., et al. 2014. Eur J Med Chem. 83: 547-60. PMID: 24996141
  8. Synthesis of N-alkoxy-substituted 2H-benzimidazoles.  |  Ansari, NH. and Söderberg, BCG. 2017. Tetrahedron Lett. 58: 4717-4720. PMID: 29503480
  9. Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones.  |  Tyagi, M., et al. 2021. J Org Chem. 86: 16582-16592. PMID: 34767366

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Bromo-1-butyne, 1 g

sc-231489
1 g
$138.00