Date published: 2026-5-8

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3-Bromo-1,2-propanediol (CAS 4704-77-2)

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Alternate Names:
α-Glycerol bromohydrin
Application:
3-Bromo-1,2-propanediol is a protecting group reagent for carbonyl functions
CAS Number:
4704-77-2
Purity:
≥97%
Molecular Weight:
154.99
Molecular Formula:
C3H7BrO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Bromo-1,2-propanediol is a bromomethylethylene ketal that can be cleaved under neutral conditions. it can act as a protecting group reagent for carbonyl functions. It functions as a flexible foundational unit, facilitating the creation of diverse compounds like dyes, and polymers. Additionally, it finds application as a reagent in the synthesis of various derivatives, including peptides and carbohydrates. This colorless liquid possesses a low boiling point and displays solubility in typical organic solvents.


3-Bromo-1,2-propanediol (CAS 4704-77-2) References

  1. Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period.  |  Vougogiannopoulou, K., et al. 2008. J Med Chem. 51: 6421-31. PMID: 18816110
  2. Radiosynthesis of the tumor hypoxia marker [18F]TFMISO via O-[18F]trifluoroethylation reveals a striking difference between trifluoroethyl tosylate and iodide in regiochemical reactivity toward oxygen nucleophiles.  |  Suehiro, M., et al. 2011. Bioorg Med Chem. 19: 2287-97. PMID: 21398131
  3. Purification and characterization of an NADH-dependent alcohol dehydrogenase from Candida maris for the synthesis of optically active 1-(pyridyl)ethanol derivatives.  |  Kawano, S., et al. 2011. Biosci Biotechnol Biochem. 75: 1055-60. PMID: 21670533
  4. Pseudomonas aeruginosa Cif defines a distinct class of α/β epoxide hydrolases utilizing a His/Tyr ring-opening pair.  |  Bahl, CD. and Madden, DR. 2012. Protein Pept Lett. 19: 186-93. PMID: 21933119
  5. Epoxide-mediated differential packaging of Cif and other virulence factors into outer membrane vesicles.  |  Ballok, AE., et al. 2014. J Bacteriol. 196: 3633-42. PMID: 25112474
  6. Controlling the origins of inflammation with a photoactive lipopeptide immunopotentiator.  |  Mancini, RJ., et al. 2015. Angew Chem Int Ed Engl. 54: 5962-5. PMID: 25800006
  7. Visualizing the Mechanism of Epoxide Hydrolysis by the Bacterial Virulence Enzyme Cif.  |  Bahl, CD., et al. 2016. Biochemistry. 55: 788-97. PMID: 26752215
  8. Enhanced PEDOT adhesion on solid substrates with electrografted P(EDOT-NH2).  |  Ouyang, L., et al. 2017. Sci Adv. 3: e1600448. PMID: 28275726
  9. Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.  |  Hvorecny, KL., et al. 2017. Structure. 25: 697-707.e4. PMID: 28392259
  10. An Improved Enzymatic Indirect Method for Simultaneous Determinations of 3-MCPD Esters and Glycidyl Esters in Fish Oils.  |  Miyazaki, K. and Koyama, K. 2017. J Oleo Sci. 66: 1085-1093. PMID: 28924085
  11. Antibiotic-Derived Lipid Nanoparticles to Treat Intracellular Staphylococcus aureus.  |  Zhang, C., et al. 2019. ACS Appl Bio Mater. 2: 1270-1277. PMID: 31750420
  12. Synthesis, Structural Characterization, and Biological Activity of New Pyrazolo[4,3-e][1,2,4]triazine Acyclonucleosides.  |  Mojzych, M., et al. 2020. Molecules. 25: PMID: 31948129
  13. Novel synthetic lipopeptides derived from Mycoplasma hyorhinis upregulate calpastatin in SH-SY5Y neuroblastoma cells and induce a neuroprotective effect against amyloid-β-peptide toxicity.  |  Kornspan, JD., et al. 2020. FEMS Microbiol Lett. 367: PMID: 32329786
  14. Determination of glycidyl esters and 3-MCPD esters in edible oils by sample pretreatment with the combination of lipase hydrolysis and modified QuEChERS for GC-MS analysis.  |  Tsai, HY., et al. 2021. J Food Drug Anal. 29: 153-167. PMID: 35696223
  15. The mechanism and substrate specificity of the NADPH:flavin oxidoreductase from Escherichia coli.  |  Fieschi, F., et al. 1995. J Biol Chem. 270: 30392-400. PMID: 8530465

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Bromo-1,2-propanediol, 5 g

sc-251948
5 g
$115.00

3-Bromo-1,2-propanediol, 25 g

sc-251948A
25 g
$397.00