Date published: 2026-5-19

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3β-Ursodeoxycholic Acid (CAS 78919-26-3)

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Alternate Names:
(3β,5β,7β)-3,7-Dihydroxycholan-24-oic Acid; 3β,7β-Dihydroxy-5β-cholan-24-oic Acid; 3β,7β-Dihydroxy-5β-cholanic Acid; 3β,7β-Dihydroxy-5β-cholanoic Acid; Isoursodeoxycholic Acid
Application:
3β-Ursodeoxycholic Acid is an anticholelithogenic
CAS Number:
78919-26-3
Molecular Weight:
392.57
Molecular Formula:
C24H40O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3β-Ursodeoxycholic Acid is a compound utilized in research focused on biliary and liver biochemistry. It is of interest in exploring the mechanisms of bile acid regulation and metabolism within the liver and gastrointestinal tract. Researchers study this compound to understand its role in modulating cholesterol solubility and transport, which is essential for the maintenance of cholesterol homeostasis. Additionally, 3β-Ursodeoxycholic Acid is used in the investigation of cellular signaling pathways influenced by bile acids, including those that impact hepatocyte function and proliferation. The compound also contributes to the study of membrane dynamics and fluidity, as bile acids interact with phospholipids in biological membranes.


3β-Ursodeoxycholic Acid (CAS 78919-26-3) References

  1. Ursodeoxycholic Acid Alters Bile Acid and Fatty Acid Profiles in a Mouse Model of Diet-Induced Obesity.  |  Zhang, Y., et al. 2019. Front Pharmacol. 10: 842. PMID: 31402868
  2. Modulation of bile acid profile by gut microbiota in chronic hepatitis B.  |  Wang, X., et al. 2020. J Cell Mol Med. 24: 2573-2581. PMID: 31925905
  3. Bacillus Subtilis Promotes the Release of 5-HT to Regulate Intestinal Peristalsis in STC Mice via Bile Acid and Its Receptor TGR5 Pathway.  |  Chen, Z., et al. 2022. Dig Dis Sci. 67: 4410-4421. PMID: 34797444
  4. Inclusion of Soluble Fiber During Gestation Regulates Gut Microbiota, Improves Bile Acid Homeostasis, and Enhances the Reproductive Performance of Sows.  |  Wu, X., et al. 2021. Front Vet Sci. 8: 756910. PMID: 34869730
  5. Gut microbiota-bile acid crosstalk contributes to the rebound weight gain after calorie restriction in mice.  |  Li, M., et al. 2022. Nat Commun. 13: 2060. PMID: 35440584
  6. Comprehensive Analysis of Gut Microbiota and Fecal Bile Acid Profiles in Children With Biliary Atresia.  |  Yang, T., et al. 2022. Front Cell Infect Microbiol. 12: 914247. PMID: 35782134
  7. Maternal Treatment with Metformin Persistently Ameliorates High-Fat Diet-Induced Metabolic Symptoms and Modulates Gut Microbiota in Rat Offspring.  |  Song, L., et al. 2022. Nutrients. 14: PMID: 36079869
  8. Mechanism of Huangqi-Honghua combination regulating the gut microbiota to affect bile acid metabolism towards preventing cerebral ischaemia-reperfusion injury in rats.  |  Wang, K., et al. 2022. Pharm Biol. 60: 2189-2199. PMID: 36307999
  9. Exclusive Enteral Nutrition Exerts Anti-Inflammatory Effects through Modulating Microbiota, Bile Acid Metabolism, and Immune Activities.  |  Xiao, F., et al. 2022. Nutrients. 14: PMID: 36364726
  10. Effect of lotus seed resistant starch on small intestinal flora and bile acids in hyperlipidemic rats.  |  Lei, S., et al. 2023. Food Chem. 404: 134599. PMID: 36444019
  11. The impact of exclusive enteral nutrition on the gut microbiome and bile acid metabolism in pediatric Crohn's disease.  |  Lv, Y., et al. 2023. Clin Nutr. 42: 116-128. PMID: 36527826
  12. Chromium exposure altered metabolome and microbiome-associated with neurotoxicity in zebrafish.  |  Yan, T., et al. 2023. J Appl Toxicol.. PMID: 36727205
  13. Abnormal urinary bile acids in a patient suffering from cerebrotendinous xanthomatosis during oral administration of ursodeoxycholic acid.  |  Koopman, BJ., et al. 1987. Biochim Biophys Acta. 917: 238-46. PMID: 3801500

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3β-Ursodeoxycholic Acid, 10 mg

sc-475550
10 mg
$307.00