Date published: 2025-12-5

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3-Azido-7-hydroxy-2H-chromen-2-one (CAS 817638-68-9)

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Alternate Names:
3-Azido-7-hydroxycoumarin
CAS Number:
817638-68-9
Molecular Weight:
203.15
Molecular Formula:
C9H5N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Azido-7-hydroxy-2H-chromen-2-one is a member of the coumarin family. Widely employed in scientific research, it serves as both a fluorescent probe for imaging and an inhibitor for specific enzymes. As a fluorescent probe, 3-Azido-7-hydroxy-2H-chromen-2-one has found extensive utility in scientific investigations. It facilitates the visualization of enzyme activity associated with drug metabolism and aids in the examination of protein structures. Furthermore, this compound functions as an inhibitor of enzymes like cytochrome P450, a critical family of enzymes involved in drug metabolism. By binding to the enzyme′s active site, 3-Azido-7-hydroxy-2H-chromen-2-one obstructs the catalytic reaction. Due to its inhibitory properties and fluorescent characteristics, 3-Azido-7-hydroxy-2H-chromen-2-one plays a vital role in studying enzyme function and protein activity. When exposed to light, it emits a fluorescent signal, enabling the imaging and visualization of enzymes and proteins.


3-Azido-7-hydroxy-2H-chromen-2-one (CAS 817638-68-9) References

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  3. Fluorescent Inhibitors as Tools To Characterize Enzymes: Case Study of the Lipid Kinase Phosphatidylinositol 4-Kinase IIIβ (PI4KB).  |  Humpolickova, J., et al. 2017. J Med Chem. 60: 119-127. PMID: 28004946
  4. Ursolic Acid, a Natural Nutraceutical Agent, Targets Caspase3 and Alleviates Inflammation-Associated Downstream Signal Transduction.  |  Ma, X., et al. 2017. Mol Nutr Food Res. 61: PMID: 28801966
  5. Chlorogenic Acid Targeting of the AKT PH Domain Activates AKT/GSK3β/FOXO1 Signaling and Improves Glucose Metabolism.  |  Gao, J., et al. 2018. Nutrients. 10: PMID: 30249058
  6. Lepidiline A Improves the Balance of Endogenous Sex Hormones and Increases Fecundity by Targeting HSD17B1.  |  Cheng, C., et al. 2020. Mol Nutr Food Res. 64: e1900706. PMID: 32239630

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Azido-7-hydroxy-2H-chromen-2-one, 25 mg

sc-483919
25 mg
$230.00

3-Azido-7-hydroxy-2H-chromen-2-one, 100 mg

sc-483919A
100 mg
$500.00

3-Azido-7-hydroxy-2H-chromen-2-one, 250 mg

sc-483919B
250 mg
$810.00

3-Azido-7-hydroxy-2H-chromen-2-one, 1 g

sc-483919C
1 g
$1940.00