Molecular structure of 3-Anilino-2-(3,4,5-Trimethoxybenzyl)acrylonitrile, CAS Number: 30078-48-9
3-Anilino-2-(3,4,5-Trimethoxybenzyl)acrylonitrile (CAS 30078-48-9)
Alternate Names:
Trimethoprim Impurity I
CAS Number:
30078-48-9
Purity:
≥98%
Molecular Weight:
324.37
Molecular Formula:
C19H20N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3-Anilino-2-(3,4,5-Trimethoxybenzyl)acrylonitrile is used as a reference standard for the drug Trimethoprim. 3-(Phenylamino)-2-(3,4,5-trimethoxybenzyl)acrylonitrile is based on its ability to act as a Lewis acid, which is a type of acid that can accept electrons from other molecules. When 3-(Phenylamino)-2-(3,4,5-trimethoxybenzyl)acrylonitrile is used as a catalyst in a reaction, it can increase the rate of reaction by stabilizing the transition state of the reaction. This is due to the electron-withdrawing effect of the 3-phenyl group, which is able to stabilize the transition state of the reaction.
3-Anilino-2-(3,4,5-Trimethoxybenzyl)acrylonitrile (CAS 30078-48-9) References
- Isolation and identification of process impurities in trimethoprim drug substance by high-performance liquid chromatography, atmospheric pressure chemical ionization liquid chromatography/mass spectrometry and nuclear magnetic resonance spectroscopy. | Lehr, GJ., et al. 1999. J Pharm Biomed Anal. 19: 373-89. PMID: 10704103
- Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes. | Goldman, JL., et al. 2016. Drug Metab Dispos. 44: 1603-7. PMID: 27457783
- Quantitative NMR (qNMR) for pharmaceutical analysis: The pioneering work of George Hanna at the US FDA. | Jaki, BU., et al. 2021. Magn Reson Chem. 59: 7-15. PMID: 32910504
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Anilino-2-(3,4,5-Trimethoxybenzyl)acrylonitrile, 1 g | sc-209536 | 1 g | $304.00 |