Date published: 2026-2-7

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3-(Aminomethyl)phenylboronic acid hydrochloride (CAS 352525-94-1)

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CAS Number:
352525-94-1
Molecular Weight:
187.43
Molecular Formula:
C7H10BNO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(3-(Aminomethyl)phenylboronic acid hydrochloride, known as AMPBH, holds significant value in diverse scientific research applications. This compound, classified as a boronic acid derivative, serves as a versatile reagent for compound synthesis, a catalyst for various reactions, and a ligand for protein and enzyme investigations. While 3-(Aminomethyl)phenylboronic acid hydrochloride brings numerous advantages and limitations to laboratory experiments, it also paves the way for promising future research directions. The scientific community has harnessed the potential of (3-(Aminomethyl)phenylboronic acid hydrochloride across a wide range of research applications. Primarily, it is employed as a pivotal reagent for synthesizing an array of compounds, including heterocyclic compounds like benzimidazoles, peptides, and peptidomimetics. At its core, (3-(Aminomethyl)phenylboronic acid hydrochloride is a boronic acid derivative that demonstrates remarkable properties. The electron-rich boron atom within this compound readily forms complexes with Lewis acids, such as amines or carboxylic acids, thereby facilitating catalytic reactions. This capacity enables the efficient synthesis of heterocyclic compounds, peptides, and peptidomimetics. Moreover, the boron atom exhibits a strong affinity for proteins and enzymes, enabling it to act as a ligand for protein and enzyme studies, elucidating their structures and mechanisms.


3-(Aminomethyl)phenylboronic acid hydrochloride (CAS 352525-94-1) References

  1. Development of phenylboronic acid-functionalized nanoparticles for emodin delivery.  |  Wang, B., et al. 2015. J Mater Chem B. 3: 3840-3847. PMID: 25960874
  2. In Situ Monitoring Intracellular Structural Change of Nanovehicles through Photoacoustic Signals Based on Phenylboronate-Linked RGD-Dextran/Purpurin 18 Conjugates.  |  Cheng, DB., et al. 2017. Biomacromolecules. 18: 1249-1258. PMID: 28269979
  3. Discovery of Highly Selective Inhibitors of the Human Constitutive Proteasome β5c Chymotryptic Subunit.  |  Zhan, W., et al. 2023. J Med Chem. 66: 1172-1185. PMID: 36608337

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-(Aminomethyl)phenylboronic acid hydrochloride, 1 g

sc-260470
1 g
$156.00

3-(Aminomethyl)phenylboronic acid hydrochloride, 5 g

sc-260470A
5 g
$624.00