Molecular structure of 3-Amino-N-cyclopentyl-benzenesulfonamide, CAS Number: 436095-38-4
3-Amino-N-cyclopentyl-benzenesulfonamide (CAS 436095-38-4)
CAS Number:
436095-38-4
Molecular Weight:
240.32
Molecular Formula:
C11H16N2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Metyrapone inhibits the biosynthesis of corticosteroids. Studies report that Metyrapone inhibits the hydroxylase activity of omega/omega-1 from the cytochrome P450-mediated prostaglandin. Has shown to block glucocorticoid synthesis via inhibition of steroid 11-beta hydroxylase (CYP11B1). Small concentrations of Metyrapone are reported to rapidly oxidize endogenous NADPH, improve oxidation of cortisol, and inhibit the reduction of cortisone in rat liver studies. Additionally, depletion of luminal NADPH has been observed in the presence of Metyrapone. Inflammatory studies in rats report that Metyrapone regulates the expression of pro-inflammatory cytokines. Metyrapone is an inhibitor of CYP3A4.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Amino-N-cyclopentyl-benzenesulfonamide, 500 mg | sc-312457 | 500 mg | $255.00 |