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Thiolutin is a sulfur-containing compound with a dithiolopyrrolone structure, notable in antifungal and antibacterial research. In research applications, thiolutin is utilized to probe the function of RNA polymerases, as it is known to inhibit both prokaryotic and eukaryotic RNA polymerase activities. This inhibition is for understanding the transcriptional processes within cells and the effects of transcriptional disruption. Studies involving thiolutin have shed light on the complex interplay between transcription factors and RNA polymerases, providing valuable insights into gene expression regulation. Furthermore, thiolutin′s ability to halt the synthesis of mRNA offers a method to explore the cellular responses to transcriptional stress, including the examination of stress response pathways and the identification of compounds with potential regulatory roles.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Amino-N-(4-fluorophenyl)benzamide, 500 mg | sc-312441 | 500 mg | $284.00 |