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Efavirenz is a nonnucleoside HIV-1 RT (HIV-1 reverse transcriptase) inhibitor which selectively inhibits the glucuronidation of 3′-Azido-3′-deoxythymidine beta-D-glucuronide, Sodium Salt (sc-220900). Studies suggest that Efavirenz binds to a distinct site of reverse transcriptase which is not the active site. In addition, Efavirenz does not competitively inhibit substrates and template primers, but decreases the enzyme′s polymerizing activity. These studies indicate that Efavirenz is also a potent inhibitor of wild-type HIV-1 RT in vitro.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Amino-3-(4-methoxy-1-naphthyl)-propanoic acid, 500 mg | sc-312332 | 500 mg | $240.00 |