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Rolipram is a selective, cell-permeableinhibitor of cAMP-specific PDE (phosphodiesterase) (PDE4, IC50=1 muM). This compound may act to inhibit PDE4 activity in human cavernosal tissue, which interrupts the signal transduction pathway of erectile response. Rolipram promotes apoptosis in HL60 cells through a cAMP-independent mechanism and may act to enhance neuronal survival. Rolipram is an inhibitor of PDE4A1 and PDE4B.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Amino-3-(2,5-dimethylphenyl)propanoic acid, 500 mg | sc-312310 | 500 mg | $180.00 |