Molecular structure of 3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate, CAS Number: 212262-04-9
3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate (CAS 212262-04-9)
Alternate Names:
1,2-bis(2-methylsulfonylsulfanylethoxy)ethane; Mts-8-O2-Mts
Application:
3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate is a homobifunctional sulfhydryl-reactive crosslinker
CAS Number:
212262-04-9
Molecular Weight:
338.48
Molecular Formula:
C8H18O6S4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate is a cross-linking reagent, sulfhydryl based.
3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate (CAS 212262-04-9) References
- Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linking compounds as molecular rulers. | Loo, TW. and Clarke, DM. 2001. J Biol Chem. 276: 36877-80. PMID: 11518701
- Vanadate trapping of nucleotide at the ATP-binding sites of human multidrug resistance P-glycoprotein exposes different residues to the drug-binding site. | Loo, TW. and Clarke, DM. 2002. Proc Natl Acad Sci U S A. 99: 3511-6. PMID: 11891276
- Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket. | Loo, TW., et al. 2006. Biochem J. 399: 351-9. PMID: 16813563
- Transmembrane segment packing of the Na(+)/Ca(2+) exchanger investigated with chemical cross-linkers. | Ren, X., et al. 2010. Biochemistry. 49: 8585-91. PMID: 20735122
- Intragenic suppressing mutations correct the folding and intracellular traffic of misfolded mutants of Yor1p, a eukaryotic drug transporter. | Pagant, S., et al. 2010. J Biol Chem. 285: 36304-14. PMID: 20837481
- Conserved Walker A cysteines 431 and 1074 in human P-glycoprotein are accessible to thiol-specific agents in the apo and ADP-vanadate trapped conformations. | Sim, HM., et al. 2013. Biochemistry. 52: 7327-38. PMID: 24053441
- Identification of the distance between the homologous halves of P-glycoprotein that triggers the high/low ATPase activity switch. | Loo, TW. and Clarke, DM. 2014. J Biol Chem. 289: 8484-92. PMID: 24523403
- Binding of the Extracellular Eight-Cysteine Motif of Opy2 to the Putative Osmosensor Msb2 Is Essential for Activation of the Yeast High-Osmolarity Glycerol Pathway. | Yamamoto, K., et al. 2016. Mol Cell Biol. 36: 475-87. PMID: 26598606
- Structural Analysis of Target Protein by Substituted Cysteine Accessibility Method. | Cai, T. and Tomita, T. 2018. Bio Protoc. 8: e2470. PMID: 34395783
- Allosteric regulation controls actin-bundling properties of human plastins. | Schwebach, CL., et al. 2022. Nat Struct Mol Biol. 29: 519-528. PMID: 35589838
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate, 10 mg | sc-209726 | 10 mg | $360.00 |