![3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid (CAS 34576-94-8) - chemical structure image](https://media.scbt.com/product/3-6-dichloro-benzobthiophene-2-carboxylic-acid-34576-94-8-structure_20_02_b_200254.jpg)
![3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid (CAS 34576-94-8) - chemical structure image](https://media.scbt.com/product/3-6-dichloro-benzobthiophene-2-carboxylic-acid-34576-94-8-structure_20_02_t_200254.jpg "Molecular structure of 3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid, CAS Number: 34576-94-8")
Molecular structure of 3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid, CAS Number: 34576-94-8
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid (CAS 34576-94-8)
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Alternate Names:
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid is also known as 3,6-dichloro-1-benzothiophene-2-carboxylate.
Application:
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) and useful biochemical for proteomics research.
CAS Number:
34576-94-8
Purity:
≥95%
Molecular Weight:
247.10
Molecular Formula:
C9H4Cl2O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid is a useful biochemical for proteomics research. It acts as an inhibitor of myeloid cell leukemia 1 (Mcl-1) with a Ki value of 59 µM for binding of FITC-Mcl-1-BH2 peptide binding to Mcl-1. It has been used as a building block in the synthesis of inhibitors of Mcl-1, the toll-like receptor 3/double-stranded RNA (TLR3/dsRNA) complex, and D-amino acid oxidase (DAO). 3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid is also known as 3,6-dichloro-1-benzothiophene-2-carboxylate.
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid (CAS 34576-94-8) References
- 3,6-dichlorobenzo[b]thiophene-2-carboxylic acid alleviates ulcerative colitis by suppressing mammalian target of rapamycin complex 1 activation and regulating intestinal microbiota. | He, QZ., et al. 2022. World J Gastroenterol. 28: 6522-6536. PMID: 36569276
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid, 500 mg | sc-276559A | 500 mg | $142.00 | |||
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid, 1 g | sc-276559 | 1 g | $199.00 | |||
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid, 5 g | sc-276559B | 5 g | $560.00 | |||
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid, 10 g | sc-276559C | 10 g | $875.00 |