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D(−)Mannitol is a sugar alcohol that can be used as an inert osmotic control substance. The uptake and phosphorylation of the compound is catalyzed by the mannitol-specific phosphoenolpyruvate-dependent phosphotransferase systems (PTS). D(−)Mannitol can interact with neutrophils and monocytes. Experiments have shown that it is able to decrease neutrophil apoptosis in vitro. The compound has been used in studies as a stimulator of cecal microbial growth and cellulolytic activity in rabbits. It has been observed that D(−)Mannitol can lower the fat digestibility and body fat accumulation in both normal and cecectomized rats, as well as upregulate monocyte HLA-DR, monocyte and neutrophil CD11b. Studies show that the D(−)Mannitol operon is repressed by the transcription factor, D(−)Mannitol operon repressor (MtlR) in Escherichia coli.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-(6-Bromo-1H-benzoimidazol-2-ylsulfanyl)-propionic acid, 500 mg | sc-310091 | 500 mg | $255.00 |