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3,5-Dimethyl-4-iodoisoxazole (CAS 10557-85-4)

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Alternate Names:
3,5-Dimethyl-4-iodoisoxazole
CAS Number:
10557-85-4
Molecular Weight:
223.01
Molecular Formula:
C5H6INO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,5-Dimethyl-4-iodoisoxazole has found use in the preparation of heterocyclic compounds and has been subject to investigation for applications in the realms of biochemistry and molecular biology. Moreover, it has been involved in the synthesis of various polymers and polysaccharides. The precise mechanism of action of 3,5-Dimethyl-4-iodoisoxazole remains not entirely elucidated however, it is speculated that this compound functions as an inhibitor of specific enzymes, such as cyclooxygenase-2 (COX-2), and also modulates the activity of certain receptors, like the serotonin receptor.


3,5-Dimethyl-4-iodoisoxazole (CAS 10557-85-4) References

  1. RECENT DEVELOPMENTS IN ISOXAZOLE CHEMISTRY.  |  KOCHETKOV, NK. and SOKOLOV, SD. 1963. Adv Heterocycl Chem. 18: 365-422. PMID: 14279528
  2. Catalyst Control in Positional-Selective C-H Alkenylation of Isoxazoles and a Ruthenium-Mediated Assembly of Trisubstituted Pyrroles.  |  Kumar, P. and Kapur, M. 2019. Org Lett. 21: 2134-2138. PMID: 30860851
  3. Dissociative ionization of 3,5-dimethyl-4-haloisoxazoles  |  K. K. Zhigulev, R. A. Khmel'nitskii & S. D. Sokolov. 1971. Chemistry of Heterocyclic Compounds. 7: 687–690.
  4. Dipole moments of some isoxazole derivatives  |  I. B. Mazheika, I. S. Yankovska, S. D. Sokolov & I. M. Yudintseva. 1972. Chemistry of Heterocyclic Compounds. 8: 419–421.
  5. A convenient synthesis of 4-substituted 3-ethoxy-5-methylisoxazoles by palladium-catalyzed coupling reactions  |  Hasse Kromann, Frank A Sløk, Tommy N Johansen, Povl Krogsgaard-Larsen. 2001. Tetrahedron. 57: 2195-2201.
  6. A new, mild one-pot synthesis of iodinated heterocycles as suitable precursors for N-heterocyclic carbene complexes  |  Manuel Iglesias a, Oliver Schuster b †, Martin Albrecht a. 2010. Tetrahedron Letters. 51: 5423-5425.
  7. Photochromism of new unsymmetrical isomeric diarylethenes bearing a pyridine group  |  Gang Liu, Ming Liu, Shouzhi Pu, Congbin Fan, Shiqiang Cui. 2012. Tetrahedron. 68: 2267-2275.
  8. Transition Metal-Mediated Functionalization of Isoxazoles: A Review  |  Dr. Suchithra Madhavan, Santosh Kumar Keshri, Prof. Manmohan Kapur. 2021. 10: 3127-3165.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,5-Dimethyl-4-iodoisoxazole, 1 g

sc-266971
1 g
$20.00

3,5-Dimethyl-4-iodoisoxazole, 5 g

sc-266971A
5 g
$51.00