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3,5-Dimethoxyphenol (CAS 500-99-2)

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Alternate Names:
Phloroglucinol dimethyl ether
Application:
3,5-Dimethoxyphenol is a phenol derivative
CAS Number:
500-99-2
Purity:
≥98%
Molecular Weight:
154.16
Molecular Formula:
C8H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,5-Dimethoxyphenol is a compound that functions as a chemical intermediate in various development processes. It acts as a substrate or reagent in the synthesis of organic compounds, participating in reactions such as esterification, etherification, and oxidation. At the molecular level, 3,5-Dimethoxyphenol undergoes specific chemical transformations, serving as a building block for the creation of more complex molecules. Its mechanism of action involves participating in chemical reactions that lead to the formation of new compounds with distinct properties. 3,5-Dimethoxyphenol′s functional role lies in its ability to undergo specific chemical modifications, contributing to the development of diverse organic substances.


3,5-Dimethoxyphenol (CAS 500-99-2) References

  1. Unusual pseudosubstrate specificity of a novel 3,5-dimethoxyphenol O-methyltransferase cloned from Ruta graveolens L.  |  Burga, L., et al. 2005. Arch Biochem Biophys. 440: 54-64. PMID: 16023070
  2. Total synthesis of garsubellin A.  |  Siegel, DR. and Danishefsky, SJ. 2006. J Am Chem Soc. 128: 1048-9. PMID: 16433500
  3. Synthesis and cosmetic whitening effect of glycosides derived from several phenylpropanoids.  |  Tanimoto, S., et al. 2006. Yakugaku Zasshi. 126: 173-7. PMID: 16508241
  4. Chemical libraries via sequential C-H functionalization of phenols.  |  Li, K. and Tunge, JA. 2008. J Comb Chem. 10: 170-4. PMID: 18237144
  5. Preliminary gas chromatography with mass spectrometry determination of 3,5-dimethoxyphenol in biological specimens as evidence of taxus poisoning.  |  Froldi, R., et al. 2010. J Anal Toxicol. 34: 53-6. PMID: 20109304
  6. [3,5-dimethoxyfenol--marker intoxication with Taxus baccata].  |  Stríbrný, J., et al. 2010. Soud Lek. 55: 36-9. PMID: 20942244
  7. Fatal poisoning with Taxus baccata: quantification of paclitaxel (taxol A), 10-deacetyltaxol, baccatin III, 10-deacetylbaccatin III, cephalomannine (taxol B), and 3,5-dimethoxyphenol in body fluids by liquid chromatography-tandem mass spectrometry.  |  Grobosch, T., et al. 2012. J Anal Toxicol. 36: 36-43. PMID: 22290751
  8. Monitoring of aglycons of yew glycosides (3,5-dimethoxyphenol, myrtenol and 1-octen-3-ol) as first indicator of yew presence.  |  Varlet, V. and Augsburger, M. 2013. Drug Test Anal. 5: 474-9. PMID: 22371422
  9. Fatal Taxus baccata ingestion with perimortem serum taxine B quantification.  |  Arens, AM., et al. 2016. Clin Toxicol (Phila). 54: 878-880. PMID: 27436403
  10. Taxus ingredients in the red arils of Taxus baccata L. determined by HPLC-MS/MS.  |  Siegle, L. and Pietsch, J. 2018. Phytochem Anal. 29: 446-451. PMID: 29424093
  11. Fatal poisoning by ingestion of Taxus Baccata leaves.  |  Pilija, V., et al. 2018. Forensic Sci Int. 290: e1-e4. PMID: 30064830
  12. Synthesis, crystal structure and determination of the pKa value of 2,6-dimethoxycyclohexa-2,5-diene-1,4-dione 1-[2-(quinolin-8-yl)hydrazone].  |  Kachi-Terajima, C., et al. 2022. Acta Crystallogr C Struct Chem. 78: 371-375. PMID: 35788500
  13. Analytical toxicology of yew constituents in human blood and urine by liquid chromatography-high-resolution tandem mass spectrometry.  |  Jacobs, CM., et al. 2023. Drug Test Anal. 15: 123-127. PMID: 35997535
  14. Suicidal yew leave ingestion--phloroglucindimethylether (3,5-dimethoxyphenol) as a marker for poisoning from Taxus baccata.  |  Musshoff, F., et al. 1993. Int J Legal Med. 106: 45-50. PMID: 8398891

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,5-Dimethoxyphenol, 5 g

sc-238695
5 g
$42.00

3,5-Dimethoxyphenol, 10 g

sc-238695A
10 g
$79.00