Date published: 2026-1-20

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3,5-Diiodo-L-tyrosine dihydrate (CAS 18835-59-1)

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CAS Number:
18835-59-1
Molecular Weight:
469.01
Molecular Formula:
C9H9I2NO32H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,5-Diiodo-L-tyrosine dihydrate is a derivative of the amino acid tyrosine, containing two iodine atoms at the 3 and 5 positions. 3,5-Diiodo-L-tyrosine dihydrate is useful biochemistry and molecular biology. It is known for its ability to mimic the behavior of tyrosine in protein structures. 3,5-Diiodo-L-tyrosine dihydrate is useful in the study of thyroid hormone synthesis and metabolism, as well as in the investigation of iodine transport and metabolism. Its unique properties make it an important reagent in the field of biochemistry, allowing for the advancement of knowledge in various areas of biology.


3,5-Diiodo-L-tyrosine dihydrate (CAS 18835-59-1) References

  1. Ultrasound-assisted enzymatic hydrolysis for iodinated amino acid extraction from edible seaweed before reversed-phase high performance liquid chromatography-inductively coupled plasma-mass spectrometry.  |  Romarís-Hortas, V., et al. 2013. J Chromatogr A. 1309: 33-40. PMID: 23972456
  2. Metal deposition by electroless plating on polydopamine functionalized micro- and nanoparticles.  |  Mondin, G., et al. 2013. J Colloid Interface Sci. 411: 187-93. PMID: 24041548
  3. Selective Identification of Organic Iodine Compounds Using Liquid Chromatography-High Resolution Mass Spectrometry.  |  Yang, Y., et al. 2016. Anal Chem. 88: 1275-80. PMID: 26653564
  4. Selection of Internal Standards for Quantitative Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis Based on Correlation Coefficients.  |  Yang, S., et al. 2019. ACS Omega. 4: 8249-8254. PMID: 31459912
  5. Differentiation of disaccharide isomers via a combination of IR and UV photodissociation mass spectrometry.  |  Du, M., et al. 2022. Rapid Commun Mass Spectrom. 36: e9218. PMID: 34740281
  6. Thyroxine-protein interactions. VII. Effect of thyroxine analogs on the binding of 125-I-thyroxine to highly purified human thyroxine-binding globulin.  |  Hao, YL. and Tabachnick, M. 1971. Endocrinology. 88: 81-92. PMID: 4991825
  7. Synthesis of L-thyroxine from 3,5-diiodo-L-tyrosine by nonenzymic transamination.  |  Shiba, T., et al. 1970. Arch Biochem Biophys. 140: 90-5. PMID: 5460186
  8. Determination of iodine species in seaweed and seawater samples using ion-pair reversed phase high performance liquid chromatography coupled with inductively coupled plasma mass spectrometry†  |  Xu Han,a Lianghui Cao,a Heyong Cheng,*b Jinhua Liub and Zigang Xu*a . 2012. Anal. Methods. 4: 3471-3477.
  9. Formation of volatile iodine compounds under hot concentrated acid conditions (nitric acid or aqua regia) and in diluted acid solutions with or without thiocyanate  |  Denis Badocco, Francesca Romanini, Valerio Di Marco, Andrea Mondin, Paolo Pastore. 2017. Polyhedron. 122: 25-28.
  10. Crystal and molecular structure stabilized by weak interaction in unique 3,5-diiodo-L-tyrosinato copper(II) complex – synthesis, experimental and theoretical studies  |  Agnieszka Wojciechowska a, Tomasz Rojek a, Magdalena Malik−Gajewska a, Maria Jerzykiewicz b, Rafał Wysokiński a, Anna Gągor c, Piotr Rytlewski d, Zbigniew Staszak e, Marek Duczmal a. 2020. Materials Science and Engineering: B. 262.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,5-Diiodo-L-tyrosine dihydrate, 25 g

sc-214178
25 g
$79.00