Date published: 2025-10-31

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3,5-Diiodo-DL-tyrosine (CAS 66-02-4)

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Alternate Names:
3,5-Diiodo-4-hydroxyphenylalanine
CAS Number:
66-02-4
Molecular Weight:
432.98
Molecular Formula:
C9H9I2NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,5-Diiodo-DL-tyrosine is a compound that is the subject of research across various scientific disciplines. In studies of iodinated biomolecules, it serves as a model to understand the impact of iodination on metabolic processes and protein structure. This compound′s incorporation into peptides and proteins can influence their physical properties and interactions, making it valuable for probing structural dynamics and function. Additionally, 3,5-Diiodo-DL-tyrosine is used in research to explore the synthesis of radiocontrast agents due to the presence of heavy iodine atoms, which are known to absorb X-rays. In the field of biochemistry, it is also important for studying thyroid hormone biosynthesis and the role of iodinated tyrosine derivatives in this pathway. The racemic mixture of D- and L-enantiomers of 3,5-Diiodo-DL-tyrosine further allows for investigations into the effects of chirality on biological activity and molecular recognition.


3,5-Diiodo-DL-tyrosine (CAS 66-02-4) References

  1. Inhibition of L-thyroxine monodeiodination by thyroxine analogs.  |  LARSON, FC. and ALBRIGHT, EC. 1961. J Clin Invest. 40: 1132-8. PMID: 13759204
  2. Selective Identification of Organic Iodine Compounds Using Liquid Chromatography-High Resolution Mass Spectrometry.  |  Yang, Y., et al. 2016. Anal Chem. 88: 1275-80. PMID: 26653564

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,5-Diiodo-DL-tyrosine, 10 mg

sc-498721
10 mg
$430.00