Molecular structure of 3,5-Dihydroxybenzoic acid, CAS Number: 99-10-5
3,5-Dihydroxybenzoic acid (CAS 99-10-5)
Alternate Names:
α-Resorcylic acid; 5-Carboxyresorcinol
CAS Number:
99-10-5
Molecular Weight:
154.12
Molecular Formula:
C7H6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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3,5-Dihydroxybenzoic acid (3,5-DHB) is a naturally occurring benzoic acid derivative abundantly found in plants, fungi, and bacteria. It holds significant importance as an intermediate in the synthesis of various biologically active compounds, including flavonoids, lignans, and coumarins. The scientific community has extensively studied 3,5-Dihydroxybenzoic acid for its vast research applications. In vitro studies have showcased the compound′s potential to inhibit cancer cell growth, reduce inflammation, and alleviate oxidative stress. The precise mechanism of action of 3,5-Dihydroxybenzoic acid remains partially understood.
3,5-Dihydroxybenzoic acid (CAS 99-10-5) References
- meso-5,5,7,12,12,14-Hexamethyl-1,4,8,11-tetraazacyclotetradecane as a building block in supramolecular chemistry; salts formed with 2,2-biphenol, 4,4-thiodiphenol, 4,4-sulfonyldiphenol, 3-and 4-hydroxybenzoic acids, 3,5-dihydroxybenzoic acid and phenylphosphonic acid; supramolecular structures in zero, one, two and three dimensions. | Gregson, RM., et al. 2000. Acta Crystallogr B. 56 (Pt 1): 39-57. PMID: 10735443
- Hydrated salts of 3,5-dihydroxybenzoic acid with organic diamines: hydrogen-bonded supramolecular structures in two and three dimensions. | Burchell, CJ., et al. 2001. Acta Crystallogr B. 57: 329-38. PMID: 11373391
- A competitive molecular recognition study: syntheses and analysis of supramolecular assemblies of 3,5-dihydroxybenzoic acid and its bromo derivative with some N-donor compounds. | Varughese, S. and Pedireddi, VR. 2006. Chemistry. 12: 1597-609. PMID: 16250059
- Aspergillus oryzae type III polyketide synthase CsyA is involved in the biosynthesis of 3,5-dihydroxybenzoic acid. | Seshime, Y., et al. 2010. Bioorg Med Chem Lett. 20: 4785-8. PMID: 20630753
- 3,5-Dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. | Liu, C., et al. 2012. J Pharmacol Exp Ther. 341: 794-801. PMID: 22434674
- Synthesis of 3,4-dihydroxypyrrolidine-2,5-dione and 3,5-dihydroxybenzoic acid derivatives and evaluation of the carbonic anhydrase I and II inhibition. | Arslan, M., et al. 2015. J Enzyme Inhib Med Chem. 30: 896-900. PMID: 25744511
- Dehydration Study of Piracetam Co-Crystal Hydrates. | Liao, X. and Zhou, N. 2018. J Pharm Sci. 107: 2804-2809. PMID: 29969589
- Structure and electrostatic properties of the pyrimethamine-3,5-dihydroxybenzoic acid cocrystal in water solvent studied using transferred electron-density parameters. | Faroque, MU., et al. 2019. Acta Crystallogr C Struct Chem. 75: 46-53. PMID: 30601130
- L-Lactate Promotes Adult Hippocampal Neurogenesis. | Lev-Vachnish, Y., et al. 2019. Front Neurosci. 13: 403. PMID: 31178678
- Apple Peel and Flesh Contain Pro-neurogenic Compounds. | Ichwan, M., et al. 2021. Stem Cell Reports. 16: 548-565. PMID: 33577796
- Biological Activities of Lichen-Derived Monoaromatic Compounds. | Do, TH., et al. 2022. Molecules. 27: PMID: 35566220
- Lactic acid induces HSPA1A expression through ERK1/2 activation. | Nonaka, M., et al. 2023. Biosci Biotechnol Biochem. 87: 191-196. PMID: 36441019
- Stability and Antibiotic Potency Improvement of Levofloxacin by Producing New Salts with 2,6- and 3,5-Dihydroxybenzoic Acid and Their Comprehensive Structural Study. | Nugrahani, I., et al. 2022. Pharmaceutics. 15: PMID: 36678753
- Whole grain metabolite 3,5-dihydroxybenzoic acid is a beneficial nutritional molecule with the feature of a double-edged sword in human health: a critical review and dietary considerations. | Wagner, W., et al. 2023. Crit Rev Food Sci Nutr. 1-19. PMID: 37096487
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,5-Dihydroxybenzoic acid, 100 g | sc-238691 | 100 g | $57.00 |