![3,5-Dichloro-4-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenylamine (CAS 73265-15-3) - chemical structure image](https://media.scbt.com/product/3-5-dichloro-4-3-chloro-5-trifluoromethyl-2-pyridinyloxyphenylamine-structure_22_96_b_229668.jpg)
![Molecular structure of 3,5-Dichloro-4-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenylamine, CAS Number: 73265-15-3 3,5-Dichloro-4-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenylamine (CAS 73265-15-3) - chemical structure image](https://media.scbt.com/product/3-5-dichloro-4-3-chloro-5-trifluoromethyl-2-pyridinyloxyphenylamine-structure_22_96_t_229668.jpg)
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Fostriecin is an antibiotic that can be found in Streptomyces pulveraceus. This compound may act to inhibit the catalytic activity of partially purified Topo II (type II topoisomerase) in a non-competitive manner. Unlike other known inhibitors of this enzyme, fosteriecin has not been observed to cause DNA strand breaks in L1210 cells, suggesting that it does not stabilize a cleavable complex. Furthermore, in the same experiment, this agent was demonstrated to cause a block in the G2 phase of the cell cycle. Fostriecin has also displayed a strong capacity to inhibit protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A).
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,5-Dichloro-4-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenylamine, 500 mg | sc-313677 | 500 mg | $100.00 | |||
3,5-Dichloro-4-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}phenylamine, 1 g | sc-313677A | 1 g | $137.00 |