Date published: 2026-4-29

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3,5-Dibromosalicylaldehyde (CAS 90-59-5)

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Application:
3,5-Dibromosalicylaldehyde is a carbonyl compounds that can be used in the synthesis of Schiff base
CAS Number:
90-59-5
Purity:
97%
Molecular Weight:
279.91
Molecular Formula:
C7H4Br2O2
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,5-Dibromosalicylaldehyde, also referred to as 3,5-DBS, is an aromatic aldehyde that has garnered significant attention in the chemical industry due to its potential applications. Scientists have extensively employed 3,5-Dibromosalicylaldehyde in various scientific research fields. It has found utility in the synthesis of diverse heterocyclic compounds, such as indoles and quinolines, serving as a valuable reagent for the synthesis of biologically active compounds. Its application extends to the synthesis of polysaccharides, other polymers, and polycarbonates. Understanding the intricate mechanism of action of 3,5-Dibromosalicylaldehyde remains an ongoing endeavor. It is currently hypothesized that the presence of bromine atoms in the molecule renders it highly reactive due to their electron-withdrawing nature. This increased reactivity allows 3,5-DBS to engage in diverse reactions with an array of compounds, including proteins and other vital biological molecules.


3,5-Dibromosalicylaldehyde (CAS 90-59-5) References

  1. Deuterium isotope effect on 13C chemical shifts of tetrabutylammonium salts of Schiff bases amino acids.  |  Rozwadowski, Z. 2006. Magn Reson Chem. 44: 881-6. PMID: 16741983
  2. Synthesis, structures and urease inhibition studies of Schiff base metal complexes derived from 3,5-dibromosalicylaldehyde.  |  Cui, Y., et al. 2012. Eur J Med Chem. 58: 323-31. PMID: 23142672
  3. Tick-borne encephalitis virus triggers inositol-requiring enzyme 1 (IRE1) and transcription factor 6 (ATF6) pathways of unfolded protein response.  |  Yu, C., et al. 2013. Virus Res. 178: 471-7. PMID: 24177270
  4. Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.  |  Huang, M., et al. 2016. Arch Virol. 161: 699-703. PMID: 26660165
  5. Pre-ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting endoplasmic reticulum stress-dependent autophagy via PERK and IRE1 signalings.  |  Feng, D., et al. 2017. J Pineal Res. 62: PMID: 28178380
  6. A new azine derivative colorimetric and fluorescent dual-channel probe for cyanide detection.  |  Yu, B., et al. 2017. Spectrochim Acta A Mol Biomol Spectrosc. 184: 249-254. PMID: 28505606
  7. RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in rats.  |  Ni, H., et al. 2018. Exp Neurol. 304: 102-113. PMID: 29518365
  8. Homer1a Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Stress After Ischemic Reperfusion Injury by Inhibiting the PERK Pathway.  |  Wei, J., et al. 2019. Front Cell Neurosci. 13: 101. PMID: 30930751
  9. The effect of halogenation of salicylaldehyde on the antiproliferative activities of {Δ/Λ-[Ru(bpy)2(X,Y-sal)]BF4} complexes.  |  Taghizadeh Shool, M., et al. 2022. Dalton Trans. 51: 7658-7672. PMID: 35510940

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,5-Dibromosalicylaldehyde, 10 g

sc-232077
10 g
$56.00