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Alamethicin (U-22324) is a membrane-permeable antibiotic that belongs to a class of membrane active peptides called peptaibols. It is known to form voltage-dependent ion channels in lipid bilayers. This property makes it useful for studying membrane biophysics and ion transport across membranes. Alamethicin is comprised of a sequence of amino acids that allow it to integrate into lipid membranes, where it then aggregates into pore-forming structures. These structures can mimic the ion channels found in biological membranes, offering insights into the mechanisms of ion selectivity and conductivity. It can increase[32P] incorporation into phosphatidylinositol-4-phosphate. It also aids in the permeabilization of sarcoplasmic reticulum vesicles.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[4-Methoxy-3-(2-propynyloxy)phenyl]acrylic acid, 500 mg | sc-310748 | 500 mg | $198.00 | |||
3-[4-Methoxy-3-(2-propynyloxy)phenyl]acrylic acid, 1 g | sc-310748A | 1 g | $269.00 |