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3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester (CAS 34071-95-9)

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Alternate Names:
N-[(4-Hydroxyhydrocinnamoyl)oxy]succinimide; N-Succinimidyl 3-(4-hydroxyphenyl)propionate
Application:
3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester is an intermediate for high 128I-labeling of proteins
CAS Number:
34071-95-9
Molecular Weight:
263.25
Molecular Formula:
C13H13NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester is a chemical reagent employed extensively in the field of bioconjugation, a process of covalently linking two molecules, which is fundamental in biological and material sciences. This compound is particularly valuable due to its reactive N-hydroxysuccinimide (NHS) ester group, which facilitates the formation of stable amide bonds with primary amine groups found on proteins, peptides, and other amine-containing molecules. Researchers utilize this ester for modifying biomolecules with phenolic moieties, which is instrumental in creating targeted probes for imaging, creating chemical delivery systems, and designing sensors. The hydroxyphenyl group of this ester can also act as a handle for further chemical modifications, such as the introduction of radiolabels or fluorophores.


3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester (CAS 34071-95-9) References

  1. Structure Activity Relationships for Derivatives of Adenosine-5'-Triphosphate as Agonists at P(2) Purinoceptors: Heterogeneity Within P(2X) and P(2Y) Subtypes.  |  Burnstock, G., et al. 1994. Drug Dev Res. 31: 206-219. PMID: 22962511
  2. Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase.  |  D'Antonio, EL., et al. 2015. Mol Biochem Parasitol. 204: 64-76. PMID: 26778112
  3. Subcellular localization of acyl carrier protein in leaf protoplasts of Spinacia oleracea.  |  Ohlrogge, JB., et al. 1979. Proc Natl Acad Sci U S A. 76: 1194-8. PMID: 286305
  4. Preparation of 125I-labeled oligosaccharide derivatives with the aid of 3-(4-hydroxyphenyl)propionic acid N-hydroxysuccinimide ester.  |  Himmelspach, K., et al. 1977. FEBS Lett. 75: 154-8. PMID: 323044
  5. Cell Dome as an Evaluation Platform for Organized HepG2 Cells.  |  Kazama, R., et al. 2022. Cells. 12: PMID: 36611862

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester, 1 g

sc-214111
1 g
$188.00

3-(4-Hydroxyphenyl)propionic acid N-hydroxysuccinimide ester, 5 g

sc-214111A
5 g
$1056.00