Molecular structure of 3-(4-Hydroxybenzylidenyl)indolin-2-one, CAS Number: 293302-14-4
3-(4-Hydroxybenzylidenyl)indolin-2-one (CAS 293302-14-4)
Application:
3-(4-Hydroxybenzylidenyl)indolin-2-one is a selective receptor tyrosine kinase (RTK) inhibitor shown to inhibit FLK-1 RTK
CAS Number:
293302-14-4
Purity:
≥98%
Molecular Weight:
237.3
Molecular Formula:
C15H11NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3-(4-Hydroxybenzylidenyl)indolin-2-one is a selective receptor tyrosine kinase (RTK) inhibitor, inhibiting FLK-1 RTK at IC50 ~3μM. Consists predominantly of the E-isomer, contains ~10% of the Z-isomer.
3-(4-Hydroxybenzylidenyl)indolin-2-one (CAS 293302-14-4) References
- Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases. | Sun, L., et al. 1998. J Med Chem. 41: 2588-603. PMID: 9651163
Inhibitor of:
EGFR, Flk-1, and Tyrosine Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-(4-Hydroxybenzylidenyl)indolin-2-one, 1 mg | sc-202412 | 1 mg | $55.00 | |||
3-(4-Hydroxybenzylidenyl)indolin-2-one, 5 mg | sc-202412A | 5 mg | $216.00 |