Molecular structure of 3,4-Dihydroxyphenylacetic acid, CAS Number: 102-32-9
3,4-Dihydroxyphenylacetic acid (CAS 102-32-9)
See product citations (3)
Alternate Names:
Homoprotocatechuic acid
CAS Number:
102-32-9
Purity:
≥98%
Molecular Weight:
168.15
Molecular Formula:
C8H8O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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3,4-Dihydroxyphenylacetic acid is a metabolite of dopamine. Used as a biomarker to assess activity of the dopaminergic system. Potent inhibitor of dopamine reuptake. Agonist of D2-like dopamine receptors. 3,4-Dihydroxyphenylacetic acid may be employed as ligand in the preparation of Mo(VI) complexes.
3,4-Dihydroxyphenylacetic acid (CAS 102-32-9) References
- Conformational preferences of 3,4-dihydroxyphenylacetic acid (DOPAC). | Lopes Jesus, AJ., et al. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 140: 54-64. PMID: 25589387
- 3,4-Dihydroxyphenylacetic acid is a predominant biologically-active catabolite of quercetin glycosides. | Tang, Y., et al. 2016. Food Res Int. 89: 716-723. PMID: 28460970
- 3,4-Dihydroxyphenylacetic acid is a potential aldehyde dehydrogenase inducer in murine hepatoma Hepa1c1c7 cells. | Liu, Y., et al. 2017. Biosci Biotechnol Biochem. 81: 1978-1983. PMID: 28828965
- Two flavonoid metabolites, 3,4-dihydroxyphenylacetic acid and 4-methylcatechol, relax arteries ex vivo and decrease blood pressure in vivo. | Pourová, J., et al. 2018. Vascul Pharmacol. 111: 36-43. PMID: 30118763
- Efficient biosynthesis of 3, 4-dihydroxyphenylacetic acid in Escherichia coli. | Li, X., et al. 2019. J Biotechnol. 294: 14-18. PMID: 30771441
- Single dose pharmacokinetics of intravenous 3,4-dihydroxyphenylacetic acid and 3-hydroxyphenylacetic acid in rats. | Zabela, V., et al. 2020. Fitoterapia. 142: 104526. PMID: 32097685
- ZIF-67 as a Template Generating and Tuning 'Raisin Pudding'-Type Nanozymes with Multiple Enzyme-like Activities: Toward Online Electrochemical Detection of 3,4-Dihydroxyphenylacetic Acid in Living Brains. | Liu, J., et al. 2020. ACS Appl Mater Interfaces. 12: 29631-29640. PMID: 32476405
- The Microbiota-Derived Metabolite of Quercetin, 3,4-Dihydroxyphenylacetic Acid Prevents Malignant Transformation and Mitochondrial Dysfunction Induced by Hemin in Colon Cancer and Normal Colon Epithelia Cell Lines. | Catalán, M., et al. 2020. Molecules. 25: PMID: 32927689
- In vitro inhibition of glutathione-S-transferase by dopamine and its metabolites, 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylacetic acid. | Crawford, RA., et al. 2021. Neurotoxicology. 86: 85-93. PMID: 34314733
- Cranberry Proanthocyanidin and Its Microbial Metabolite 3,4-Dihydroxyphenylacetic Acid, but Not 3-(4-Hydroxyphenyl)-Propionic Acid, Partially Reverse Pro-Inflammatory microRNA Responses in Human Intestinal Epithelial Cells. | Lofft, Z., et al. 2022. Mol Nutr Food Res. 66: e2100853. PMID: 35112478
- Ethanol concentration induces production of 3,4-dihydroxyphenylacetic acid and homovanillic acid in mouse brain through activation of monoamine oxidase pathway. | Jamal, M., et al. 2022. Neurosci Lett. 782: 136689. PMID: 35598694
- 3,4-Dihydroxyphenylethanol and 3,4-dihydroxyphenylacetic acid affect the aggregation process of E46K variant of α-synuclein at different extent: Insights into the interplay between protein dynamics and catechol effect. | Fongaro, B., et al. 2022. Protein Sci. 31: e4356. PMID: 35762714
- 3,4-Dihydroxyphenylacetic acid ameliorates gut barrier dysfunction via regulation of MAPK-MLCK pathway in type 2 diabetes mice. | Liu, M., et al. 2022. Life Sci. 305: 120742. PMID: 35777584
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,4-Dihydroxyphenylacetic acid, 5 g | sc-232010 | 5 g | $20.00 |