3,4-Di-O-acetyl-1,6-anhydro-2-O-p-toluenesulfonyl-β-D-glucopyranose (CAS 84207-46-5)

3,4-Di-O-acetyl-1,6-anhydro-2-O-p-toluenesulfonyl-β-D-glucopyranose, a complex carbohydrate derivative, serves as a pivotal tool in glycobiology research, particularly in the synthesis of structurally defined oligosaccharides and glycoconjugates. This compound plays a critical role in carbohydrate chemistry due to its strategic placement of protecting groups, including acetyl and p-toluenesulfonyl functionalities, which provide regioselectivity and stability during glycosylation reactions. Mechanistically, 3,4-di-O-acetyl-1,6-anhydro-2-O-p-toluenesulfonyl-β-D-glucopyranose enables the controlled activation and manipulation of specific hydroxyl groups within the carbohydrate scaffold, facilitating the stepwise assembly of oligosaccharides with precise stereochemical and regiochemical control. Moreover, this compound has been instrumental in the synthesis of biologically relevant carbohydrate motifs, such as glycosaminoglycan fragments and glycolipids, for studying carbohydrate-protein interactions and cellular recognition processes. Additionally, 3,4-di-O-acetyl-1,6-anhydro-2-O-p-toluenesulfonyl-β-D-glucopyranose has found applications in the development of carbohydrate-based materials, such as glycan microarrays and carbohydrate-functionalized surfaces, for investigating carbohydrate-mediated biological processes and developing novel biomedical applications. Overall, this compound serves as a valuable synthetic tool for advancing our understanding of carbohydrate structure-function relationships and their implications in various biological processes.