Date published: 2025-9-26

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3,4,7-Trimethyl-1H-indole-2-carboxylic acid (CAS 876715-79-6)

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CAS Number:
876715-79-6
Molecular Weight:
203.24
Molecular Formula:
C12H13NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Thiostrepton is a cyclic peptide antibiotic, densely packed with thiazoles and other structurally intriguing moieties. It exhibits antibiotic activity through blockade of ribosome turnover after an elongation step in protein synthesis by inhibiting both the dissociation of elongation factor G (EF-G) from the ribosome and the release of inorganic phosphate from EF-G following GTP hydrolysis. Thiostrepton is also described to show efficacy against cancer cell growth through downregulation of the forkhead box M1 (FOXM1) transcription factor, overexpressed in many malignancies. Additionally, it is an inhibitor of FOXM1.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,4,7-Trimethyl-1H-indole-2-carboxylic acid, 500 mg

sc-313653
500 mg
$260.00